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Serum Total Antioxidant Activity after Myocardial Infarction

Annals of Clinical Biochemistry International Journal of Laboratory MedicinePublished 1 January 1997
Nicholas J. Miller, John D. Johnston, Clifford S. Collis, Catherine Rice‐Evans
Citations51
SJR quartileQ3
SJR score0.49
SNIP0.93

TL;DR

A decline in the ‘antioxidant gap’ after myocardial infarction was associated with a significantly higher mortality, and no significant changes in serum total antioxidant activity were observed in either group of patients between admission, day 1 and day 2.

Abstract

Serum total antioxidant activity (TAA), albumin and uric acid were measured on admission, and for the next 2 days in 56 patients suffering myocardial infarction, 20 of whom received streptokinase. The 'antioxidant gap', the difference between the serum TAA and the sum of the serum albumin and uric acid activity, was calculated. No significant changes in serum total antioxidant activity were observed in either group of patients between admission, day 1 and day 2. However, a decline in the 'antioxidant gap' after myocardial infarction was associated with a significantly higher mortality.

Keywords

Biochemistry, Genetics and Molecular BiologyMedicineNursing