login

Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study

Biological PsychiatryPublished 1 February 2000
Dorothee P. Auer, Benno Pütz, Eduard Kraft, Bernadette Lipinski, Julia Schill, Florian Holsboer
Citations565
SJR quartileQ1
SJR score4.68
SNIP2.24

TL;DR

This study suggests a possible role of altered glutamatergic neurotransmission within the anterior cingulate in the pathogenesis of mood disorders.

Abstract

This study suggests a possible role of altered glutamatergic neurotransmission within the anterior cingulate in the pathogenesis of mood disorders. The otherwise unremarkable findings of major brain metabolites confirms lack of neurodegenerative or membrane metabolic changes in major depression.

Keywords

MedicineNeuroscience