Treatment of hepatorenal syndrome
The American Journal of SurgeryPublished 1 March 1980
Michael L. Schwartz, Stephen B. Vogel
Citations18
SJR quartileQ1
SJR score0.95
SNIP1.17
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Abstract
Five patients with hepatorenal syndrome were treated with a LeVeen peritoneovenous shunt and furosemide. Four of the five patients responded immediately with urinary volumes in excess of 2 liters on the day of surgery and the subsequent 3 postoperative days. Urinary sodium excretion increased from 5 to 122 mEq/liter after insertion of a peritoneovenous shunt. Body weight decreased by 7.7 kg in 1 week. Serum creatinine decreased from 4.0 to 1.8 mg/dl in 1 week. There were two long-term survivors. Peritoneovenous shunting is an effective method of reversing the renal component in the hepatorenal syndrome.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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The decreased E PAH and associated renal functional changes noted in some patients with cirrhosis are explained best by a hemodynamic alteration involving renal cortical vasoconstriction with relative increase in medullary blood flow.
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44 Citations1977S Wapnick
30 consecutive patients with cirrhosis of the liver complicated by refractory ascites, hepatorenal syndrome, or both, received a LeVeen peritoneal-venous shunt and demonstrated decreased abdominal girth, decreased body weight, and increased urinary flow after surgery.
GutThe effect of octapressin on renal and intrarenal blood flow in cirrhosis of the liver
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PubMedHepatorenal syndrome: reversal by peritoneovenous shunt.
37 Citations1977Fullen Wd
Two patients with hepatorenal syndrome were treated by insertion of a peritoneovenous shunt and the renal deficit was corrected rapidly in both cases, resulting in minimal ascites 18 months after shunt.
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The effect of ascitic-fluid infusion and furosemide administration alone and in combination was studied acutely in eight patients with massive ascites.
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34 Citations1977Terence R. Pladson
A patient whose renal failure resolved after placement of a peritoneovenous shunt is described, a major advantage of this device is that it can be inserted with the patient under local anesthesia with minimal surgical risk.
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A patient whose renal failure resolved after placement of a peritoneovenous shunt is described, a major advantage of this device is that it can be inserted with the patient under local anesthesia with minimal surgical risk.
JAMAPeritoneovenous (LeVeen) Shunt
26 Citations1978Marlys H. Witte
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Annals of Internal MedicinePlasma Volume and Renal Circulatory Function in Cirrhosis
25 Citations1967RANDOLPH M. MCCLOY, WILLIAM P. BALDUS +2 more
Excerpt Diminutions in plasma volume or effective extracellular fluid volume have been proposed as explanations for renal circulatory failure in patients with cirrhosis.
PubMedThe hepatorenal syndrome.
7 Citations1976Metz Rj, Tompkins Rk
Therapy for the hepatorenal syndrome generally has failed to ameliorate extremely unfavorable mortality rates; factors as the effects of plasma volume expansion; various pharmacologic agents, including dopamine, Octopressin and metaraminol; portacaval shunt; transplantation of the liver, and steroids are discussed.