A note on the failure of CGP 19835 A (MTP-PE) to influence the course of influenza A2 infection in human volunteers
Antiviral ResearchPublished 1 August 1989
Peter G. Higgins, G. I. Barrow, Alan W. Galbraith, Heiner Frost, D. A. J. Tyrrell
Citations8
SJR quartileQ1
SJR score1.20
SNIP0.93
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TL;DR
A single dose of the immunomodulator CGP A (MTP-PE) given intranasally to human volunteers 24 h prior to challenge with influenza A2 virus failed to protect against infection or ameriolate any subsequent illness.
Abstract
A single dose of the immunomodulator CGP A (MTP-PE) given intranasally to human volunteers 24 h prior to challenge with influenza A2 virus failed to protect against infection or ameriolate any subsequent illness.
Keywords
Immunology and MicrobiologyMedicine
ScienceProtection of Mice Against Fatal Herpes Simplex Type 2 Infection by Liposomes Containing Muramyl Tripeptide
67 Citations1985Wayne C. Koff, S D Showalter +2 more
These findings suggest that the systemic activation of macrophages by liposomes containing an immunomodulator can lead to prophylaxis of severe infections caused by herpesviruses.
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29 Citations1986Felix M. Dietrich, H. K. Hochkeppel +1 more
Muramyl tripeptide-phosphatidylethanolamine displays prophylactic antiviral activity in mice infected with influenza viruses A and B, parainfluenza 1 virus or herpes simplex type 1 viruses and in guinea pigs infected with HSV/2 viruses.
