Thrombotic phenomena associated with intravenous cocaine
Journal of the American Academy of DermatologyPublished 1 February 1987
Madalene C.Y. Heng, George Haberfeld
Citations53
SJR quartileQ1
SJR score1.31
SNIP1.44
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TL;DR
A patient with infarctive skin lesions and associated involvement of the kidney and liver caused by an intravenous overdose of cocaine is described, with thrombotic tendency related to endothelial cell damage from prolonged vasoconstriction or cocaine toxicity.
Abstract
A patient with infarctive skin lesions and associated involvement of the kidney and liver caused by an intravenous overdose of cocaine is described. The thrombotic tendency may possibly be related to endothelial cell damage from prolonged vasoconstriction or cocaine toxicity, with disturbance of prostacyclin-thromboxane balance and enhancement of platelet aggregation and thrombotic tendency.
Keywords
MedicinePharmacology, Toxicology and Pharmaceutics
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