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Drug-Dependent Requirement of Hippocampal Neurogenesis in a Model of Depression and of Antidepressant Reversal

Biological PsychiatryPublished 12 April 2008
Alexandre Surget, Michael Saxe, Samuel Leman, Yadira Ibargüen-Vargas, Sylvie Chalon, Guy Griebel
Citations532
SJR quartileQ1
SJR score4.68
SNIP2.24

TL;DR

It is suggested that hippocampal neurogenesis might be used by the monoaminergic ADs to counteract the effects of stress, whereas similar effects could be achieved by directly targeting the HPA axis and related neuropeptides.

Abstract

Hippocampal neurogenesis might thus be used by the monoaminergic ADs to counteract the effects of stress, whereas similar effects could be achieved by directly targeting the HPA axis and related neuropeptides.

Keywords

PsychologyNeuroscience