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Distribution and properties of glucagon immunoreactivity in the digestive tract of various mammals: An immunohistochemical and immunochemical study

Histochemistry and Cell BiologyPublished 1 January 1975
Lars Larsson, Jens J. Holst, R. H�kanson, F. Sundler
Citations197
SJR quartileQ1
SJR score0.75
SNIP0.71

TL;DR

Numerous epithelial cells in the oxyntic gland area of the stomach of cat and dog appear to store pancreatic-type glucagon, as evidenced by immunohistochemistry and—in the case of the dog—also by radioimmunoanalysis.

Abstract

Numerous epithelial cells in the oxyntic gland area of the stomach of cat and dog appear to store pancreatic-type glucagon, as evidenced by immunohistochemistry and--in the case of the dog--also by radioimmunoanalysis. No glucagon immunoreactive cells are found in the antropyloric mucosa. Disseminated cells in the intestinal mucosa store gut-type glucagon. In all species studied, these cells predominate in ileum and colon.

Keywords

Medicine