The Urinary Concentrating Mechanism
New England Journal of MedicinePublished 4 November 1976
Rex L. Jamison, Roy H. Maffly
Citations104
SJR quartileQ1
SJR score19.08
SNIP13.47
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TL;DR
It is necessary to select patients suitable for vaginal or laparoscopic mesh placement for urinary concentrating dysfunction on the basis of prior history and once they provide informed consent for surgery.
Abstract
Disorders of the urinary concentrating mechanism vary widely in their clinical importance. At one extreme, they may simply represent an inconvenience to the patient who has to arise several times each night to urinate. At the other extreme, they cause life-threatening fluid losses: in one memorable instance, a patient with diabetes insipidus was reported to excrete 47 liters in one day. Between these extremes, impaired urinary concentration may be the first clue to the presence of a systemic disturbance, such as hypercalcemia, Sjögren's syndrome or amyloidosis.The factors responsible for the kidney's remarkable ability to regulate daily water output from . . .
Keywords
Medicine
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