Association between selective serotonin reuptake inhibitors and upper gastrointestinal bleeding: population based case-control study
BMJPublished 23 October 1999Open access
Francisco J. de Abajo, Luis A. Garcı́a Rodrı́guez, D. Montero
Citations450
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TL;DR
The concurrent use of non-steroidal anti-inflammatory drugs or aspirin with selective serotonin reuptake inhibitors greatly increases the risk of upper gastrointestinal bleeding.
Abstract
Selective serotonin reuptake inhibitors increase the risk of upper gastrointestinal bleeding. The absolute effect is, however, moderate and about equivalent to low dose ibuprofen. The concurrent use of non-steroidal anti-inflammatory drugs or aspirin with selective serotonin reuptake inhibitors greatly increases the risk of upper gastrointestinal bleeding.
Keywords
Medicine
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