Breast-Feeding and Optimal Visual Development
Journal of Pediatric Ophthalmology & StrabismusPublished 1 January 1993
Eileen E. Birch, David G. Birch, Dennis R. Hoffman, Linda Hale, Mary Everett, Ricardo Uauy
Citations215
SJR quartileQ2
SJR score0.46
SNIP0.58
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Abstract
The goal of the present study was to determine whether dietary supply of omega-3 essential fatty acid (EFA) influences visual development in healthy pre-term and full-term infants. Visual status was examined in human milk-fed infants (ample dietary omega-3 EFA supply) and corn oil-based formula-fed infants (no dietary omega-3 EFA; standard formula prior to 1987). At 57 weeks postconception (4 months adjusted age), both pre-term and full-term human milk-fed infants had significantly better visual evoked potential (VEP) and forced-choice preferential-looking (FPL) acuity than formula-fed infants. Acuity was correlated with a dietary omega-3 sufficiency index from red blood cell membranes obtained at 57 weeks postconception. At 36 months, full-term human milk-fed children had significantly better random dot stereo acuity and letter matching ability than formula-fed children. Stereo acuity and performance on the letter matching test were correlated with a dietary omega-3 sufficiency index from red blood cell membranes obtained at 4 months. These results suggest that dietary omega-3 fatty acids play an important role in visual development.
Keywords
PsychologyMedicineNursing
The Journal of the Acoustical Society of AmericaTransformed Up-Down Methods in Psychoacoustics
5,533 Citations1971Harry Levitt
A broad class of up‐down methods used in psychoacoustics with due emphasis on the related problems of parameter estimation and the efficient placing of observations is described, including examples where conventional techniques are inapplicable.
The LancetBreast milk and subsequent intelligence quotient in children born preterm
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Children who had consumed mother's milk in the early weeks of life had a significantly higher IQ at 71/2-8 years than did those who received no maternal milk and this advantage remained even after adjustment for differences between groups in mother's education and social class.
Early Human DevelopmentIntrauterine fatty acid accretion rates in human brain: implications for fatty acid requirements
781 Citations1980M. Thomas Clandinin, J.E. Chappell +4 more
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The development of the human eye
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Pediatric ResearchEffect of Dietary Omega-3 Fatty Acids on Retinal Function of Very-Low-Birth-Weight Neonates
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An essential role for ω-3 fatty acids in retinal development is supported by electroretinogram results and the fatty acid composition of plasma and red blood cell (RBC) lipids were similar for all groups on entry but marked dietinduced differences were found after feeding the study diets.
OphthalmologyThe Morphological Development of the Human Fovea
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As judged by anatomical criteria and compared to normal adult foveas similarly processed, the human fovea reaches maturity between 15 and 45 months of age.
PEDIATRICSNutritional Needs of Low-Birth-Weight Infants
515 Citations1985Committee on Nutrition
Aiming for a postnatal growth that approximates the in utero growth of a normal fetus at the same postconception age appears to be the most logical approach at present.
PubMedDietary essential fatty acid supply and visual acuity development.
434 Citations1992Eileen E. Birch, David G. Birch +2 more
The results suggest that dietary omega-3 fatty acid supply may play an important role in early human visual development.
Journal of Biological ChemistryEffect of Saturated and Unsaturated Fatty Acids on the Desaturation in Vitro of Palmitic, Stearic, Oleic, Linoleic, and Linolenic Acids
406 Citations1966Rodolfo R. Brenner, Raúl O. Peluffo
Quantitative oxidative desaturation of labeled palmitic, stearic, oleic, linoleic, and linolenic acids was studied by gas-liquid radiochromatography after incubation of the acids in a medium containing adenosine triphosphate, reduced nicotinamide adenine dinucleotide, MgCl2, coenzyme A, glutathione, Nicotinamide, NaF, and NaCN in oxygen at pH 7 and 35°.
Early Human DevelopmentExtrauterine fatty acid accretion in infant brain: implications for fatty acid requirements
403 Citations1980M T Clandinin, J.E. Chappell +4 more
Developmental changes in fatty acid components of whole brain and cerebellum are quantitatively relevant to estimation of the minimal extrauterine fatty acid requirements of the human neonate.
PubMedRetinal development in very-low-birth-weight infants fed diets differing in omega-3 fatty acids.
342 Citations1992David G. Birch, Eileen E. Birch +2 more
It is suggested that retinal function varies with the dietary supply of omega-3 fatty acids in VLBW infants.
American Journal of Clinical NutritionDocosahexaenoic acid status of preterm infants at birth and following feeding with human milk or formula
291 Citations1986SE Carlson, P Rhodes +1 more
The docosahexaenoic acid (DHA) status of preterm infants (less than 32 wk gestation) was measured as the molar percent of DHA in individual red blood cell phospholipids immediately following delivery, after infants were receiving greater than 60 kcal X kg X day of energy from oral-gastric feedings, and at a mean of 7 wk later.
Early Human DevelopmentFatty acid utilization in perinatal de novo synthesis of tissues
270 Citations1981M T Clandinin, J.E. Chappell +3 more
The fatty acid content of fetal tissues was utilized to estimate essential fatty acid accretion during intrauterine growth and it was concluded that some 70 and 78% of these net whole body accretion rates for essential fatty acids represent omega-6 and omega-3 fatty Acid accretion in the adipose organs.
Nutrition Reviewsn-3 Fatty Acids in the Brain and Retina: Evidence for Their Essentiality
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Experimental Eye ResearchA reinvestigation of the fatty acid content of bovine, rat and frog retinal rod outer segments
235 Citations1979William L. Stone, Christopher C. Farnsworth +1 more
The results indicate that if adequate levels of vitamin E are present the maintenance of antioxidant conditions during preparation procedure is not a highly critical factor in determining ROS PUFA content.
Developmental Medicine & Child NeurologyFeeding in Infancy and Later Ability and Attainment: a Longitudinal Study
199 Citations1978Bryan Rodgers
Attainment tests completed by members of the National Survey of Health and Development (1946 birth cohort) showed that those who had been entirely bottle‐fed in infancy scored significantly lower than those who have been entirely breast‐fed.
European Journal of PediatricsEffects of dietary long-chain polyunsaturated fatty acids on the essential fatty acid status of premature infants
178 Citations1989B. Koletzko, Erik Berg Schmidt +3 more
It is concluded that the essential fatty acid status of formula-fed premature infants can be improved by a supplementation of omega-6- and omega-3-LCP.
Experimental Eye ResearchPolyunsaturated fatty acids of photoreceptor membranes
149 Citations1974Robert E. Anderson, R. M. Benolken +3 more
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid MetabolismRegulation of unsaturated fatty acids biosynthesis 1. Effect of unsaturated fatty acid of 18 carbons on the microsomal desaturation of linoleic acid into γ-linolenic acid
146 Citations1969Rodolfo R. Brenner, Raúl O. Peluffo
The desaturation of oleic, linoleic and α-linolenic acids may be regulated by competitive reactions among the three acids, other acids, their reaction products or by feed-back inhibition.
LipidsEssentiality of dietary ω3 fatty acids for premature infants: Plasma and red blood cell fatty acid composition
145 Citations1992Dennis R. Hoffman, Ricardo Uauy
The results support the essentiality of ω3 fatty acids for preterm infants to obtain fatty acid profiles comparable to infants receiving human milk and should be supplemented with ω2 long-chain polyunsaturated fatty acids including LCP.
Pediatric ResearchEffect of Fish Oil Supplementation on the n-3 Fatty Acid Content of Red Blood Cell Membranes in Preterm Infants
138 Citations1987Susan E. Carlson, Philip G. Rhodes +2 more
Infants supplemented with MaxEPA maintained the same weight percent of phospholipid (phosphatidylethanolanine, phosphatidylcholine, and phospharidylserine) DHA as at enrollment, and the pattern of red blood cell phospholIPid fatty acids in supplemented infants was similar to that reported for preterm infants fed human milk.
British Journal Of NutritionA comparison of the influence of breast-feeding and bottle-feeding on the fatty acid composition of the erythrocytes
125 Citations1979T. A. B. Sanders, D. J. Naismith
The proportion of long-chain polyunsaturated derivatives of linoleic and linolenic acids in the erythrocyte lipids of infants fed a cow's milk formula was lower than in breast-fed infants.
PubMedThe metabolism of omega-3 polyunsaturated fatty acids in the eye: the possible role of docosahexaenoic acid and docosanoids in retinal physiology and ocular pathology.
108 Citations1989Nicolás G. Bazán
Docosanoid, oxygenated derivatives of DHA that resemble eicosanoids, may well prove to be unique mediators of physiological processes in the central nervous system, including the retina, and may play a role in some ocular pathologies.
American Journal of Clinical NutritionPlasma and red blood cell fatty acids of low-birth-weight infants fed their mother’s expressed breast milk or preterm-infant formula
78 Citations1990SM Innis, KD Foote +2 more
It is suggested that formula with greater than or equal to 2% 18:3n-3 and a ratio of 18:2n-6 to 18:4n-4 similar to that of human milk may permit incorporation of n-3 fatty acids in LBW infant tissues equivalent to that from human milk.
PubMedStructural development of the visual system of man.
73 Citations1984Garey Lj
In both monkey and man these developmental changes manifested by an initial overgrowth of pre- and postsynaptic elements and a subsequent "pruning" to mature levels correspond to a period of physiological and behavioural changes in visual function.
Journal of Pediatric Gastroenterology and NutritionChanges in the Fatty Acids Pattern of Red Blood Cell Phospholipids Induced by Type of Milk, Dietary Nucleotide Supplementation, and Postnatal Age in Preterm Infants
54 Citations1988M.L. Pita, María Reyes Pérez Fernández +5 more
The fatty acid profile of red blood cell phospholipids and the totalospholipid and cholesterol contents of erythrocyte membrane in preterm infants in the first month of life were studied and no significant differences were found between human milk and nucleotide milk formula infants.
Journal of Pediatric Ophthalmology & StrabismusColor Vision Screening of Young Children
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