A randomised trial of high-dose chemotherapy in the salvage treatment of patients failing first-line platinum chemotherapy for advanced germ cell tumours
Annals of OncologyPublished 31 May 2005
J L Pico, Giovanni Rosti, A. Kramar, H. Wandt, Vladimír Koza, Roberto Salvioni
Citations287
SJR quartileQ1
SJR score19.07
SNIP10.48
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TL;DR
The single cycle of high-dose salvage chemotherapy after three cycles of standard dose chemotherapy had no effect on treatment outcomes, and results suggest that data from uncontrolled studies should not be used to justify routine use of a toxic and expensive treatment without confirmation in a randomised trial.
Abstract
The single cycle of high-dose salvage chemotherapy after three cycles of standard dose chemotherapy had no effect on treatment outcomes. These results suggest that data from uncontrolled studies should not be used to justify routine use of a toxic and expensive treatment without confirmation in a randomised trial.
Keywords
Medicine
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