Caffeine and alcohol as risk factors for sudden infant death syndrome
Archives of Disease in ChildhoodPublished 1 August 1999Open access
Bernt Alm, Göran Wennergren, G Norvenius, R. Skjarven, Nina Øyen, Karin Helweg‐Larsen
Citations59
SJR quartileQ1
SJR score0.97
SNIP1.16
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TL;DR
Caffeine during or after pregnancy was not found to be an independent risk factor for SIDS after adjustment for maternal age, education, parity, and smoking during pregnancy.
Abstract
Caffeine during or after pregnancy was not found to be an independent risk factor for SIDS after adjustment for maternal age, education, parity, and smoking during pregnancy. Heavy postnatal but not prenatal intake of alcohol by the mother increased the risk.
Keywords
MedicineNeuroscience
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Doctors should keep in mind the possibility that an excessive intake of caffeine may be a factor in otherwise unexplainable spontaneous abortion or perinatal mortality.
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It is suggested that heavy caffeine consumption increases the risk for fetal growth retardation.
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Results indicate that caffeine, even in low doses which at the lower levels of the experiment may approximate to the daily human intake of a heavy coffee consumer, suppresses growth of embryonic and fetal tissues.
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Reducing heavy caffeine intake during pregnancy could be another way to lessen the risk of SIDS, which has been associated with fetal harm and now SIDS.
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64 Citations2010N Furuhashi, Sinzi Sato +4 more
The heavy coffee drinkers among the pregnant women had high rates of spontaneous abortion, chromosomal abnormality and congenital multi-anomalies, and the multiple socioeconomic variables might be more important than any direct effect of caffeine.
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62 Citations1991Stephen R. Kandall, Judith Gaines
Because of reports in the medical literature and lay press linking maternal substance use to subsequent SIDS, specific drug-related counseling issues must be recognized by health professionals to provide effective intervention in the event of a SIDS death.
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56 Citations1983T.F.X. Collins, John J. Welsh +2 more
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Both first- and second-trimester consumption of 1-150 mg/day were associated with a modestly increased risk of preterm delivery, while no association was found at higher consumption levels, as is true in most previous studies.
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Results indicate that caffeine feeding can have a positive effect on porcine mammary gland development as well as milk yield.
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11 Citations1994Astrid Nehlig, G Debry
It appears that maternal coffee or caffeine consumption during gestation and/or lactation does not seem to have measurable consequences on the fetus of the newborn, as long as ingested quantities remain moderate, and pregnant mothers should be advised to limit their coffee and caffeine intake.
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There were no significant differences in the number of apnoeic pauses in the quantities of periodic breathing or in the heart and respiratory rates during regular breathing between the siblings and the controls.
Natural ToxinsInteraction of dimethylsulfoxide and arachidonic acid with the teratogenic effects of caffeine in mice
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A correlation between caffeine-induced FH and CP is suggested; a role for increased hematomagenic effects of DMSO in its potentiation of the cleft-palatogenic effect of caffeine; and absence of a role of AA-mediated effects of MGC in the causation of CA-induced CP and other malformations are suggested.
