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Dopamine D4 receptor gene polymorphism and personality traits in healthy volunteers

European Archives of Psychiatry and Clinical NeurosciencePublished 21 August 2000
Malin Persson, D. Wassermann, T. Geijer, Amos Frisch, Rivka Rockah, Elena Michaelovsky
Citations28
SJR quartileQ1
SJR score1.59
SNIP1.37

TL;DR

The present study did not yield evidence for an association between Extraversion and the dopamine receptor D4 polymorphism.

Abstract

An association between long alleles of a variable number tandem repeat (VNTR) polymorphism in the dopamine receptor D4 gene and the extraversion related personality traits Excitement and Novelty Seeking has been reported in healthy subjects. In an attempt to replicate the previous findings, 256 healthy Caucasian volunteers were analysed for a potential relationship between the dopamine receptor D4 exon III VNTR polymorphism and Extraversion as assessed by the Revised Neo Personality Inventory (NEO PI-R). The present study did not yield evidence for an association between Extraversion and the dopamine receptor D4 polymorphism.

Keywords

PsychologyNeuroscience