Dementia of the Alzheimer Type
Annual Review of NeurosciencePublished 1 March 1980
Roggie Terry, Peter Davies
Citations521
SJR quartileQ1
SJR score7.11
SNIP3.24
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
In recent years most investigators have agreed that it is essentially identical to the most common form of senile dementia, which is thus calledSenile dementia of the Alzheimer type, or SDAT, which was originally described as a presenile disor der occurring before age 65.
Abstract
The brain's default mode network consists of discrete, bilateral and symmetrical cortical areas, in the medial and lateral parietal, medial prefrontal, and medial and lateral temporal cortices of the human, nonhuman primate, cat, and rodent brains. Its ...Read More
Keywords
MedicineNeuroscience
Journal of Psychiatric Research“Mini-mental state”
86,858 Citations1975Marshal F. Folstein, Susan E. Folstein +1 more
A simplified, scored form of the cognitive mental status examination, the “Mini-Mental State” (MMS) which includes eleven questions, requires only 5-10 min to administer, and is therefore practical to use serially and routinely.
The British Journal of PsychiatryThe Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects
4,123 Citations1968G. Blessed, B. E. Tomlinson +1 more
The expectation of mental disorder shows a steep increase with advancing chronological age, and beyond 75 years a large part of this increase is accounted for by disorders associated with degenerative changes in the central nervous system for which the authors lack remedies at the present time.
Brain ResearchNeurotransmitter-related enzymes in senile dementia of the alzheimer type
636 Citations1979Peter Davies
Large, widespread reductions in the activities of ChAT and AChE were found in tissues from SDAT cases, while GAD activities were reduced in 3 of the 20 regions investigated.
The Journal of Clinical PsychiatryA Randomized Placebo-Controlled Trial of Risperidone for the Treatment of Aggression, Agitation, and Psychosis of Dementia
464 Citations2003Henry Brodaty, David Ames +7 more
Treatment with low-dose risperidone resulted in significant improvement in aggression, agitation, and psychosis associated with dementia.
The LancetACCELERATED AGEING OR SELECTIVE NEURONAL LOSS AS AN IMPORTANT CAUSE OF DEMENTIA?
327 Citations1979J. A. Spillane, G. Curzon +6 more
It is suggested that Alzheimer's disease is a primary degenerative nerve-cell disorder and not the result of accelerated ageing, and there is selective loss of neocortical cholinergic neurones.
The Primary Care Companion to The Journal of Clinical PsychiatryTreatment Guidelines for Alzheimer's Disease
58 Citations2007David Geldmacher
Revised treatment guidelines for Alzheimer's disease should address newer medications and more recent outcomes considerations, as well as provide guidance on how long to continue and when to discontinue pharmacotherapy for AD.
Progress in brain researchStudies in Ageing of the Brain.
30 Citations1973James H. Austin, Robert W. Rinehart +5 more
It appears that some local factor is associated with the discrete increase of silicon in the Alzheimer plaque, and total silicon showed no consistent corresponding increase in the cerebrum as a whole, in various systemic organs, or in various body fluids.
Archives of Neurology And PsychiatryACID PHOSPHATASE IN THE SENILE BRAIN
27 Citations1949H Josephy
The authors discuss the possibility that the enzyme may be liberated and describe a method by which acid phosphatase, too, can be made visible in sections.
