Dual Secondary Amine/N‐Heterocyclic Carbene Catalysis in the Asymmetric Michael/Cross‐Benzoin Cascade Reaction of β‐Oxo Sulfones with Enals
European Journal of Organic ChemistryPublished 15 June 2011
Dieter Enders, André Grossmann, He Huang, Gerhard Raabe
Citations83
SJR quartileQ2
SJR score0.56
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Abstract
Abstract Polyfuncionalized cyclopentanones with three contiguous stereogenic centers were formed in good to excellent yields and stereoselectivities by utilizing a secondary amine/N‐heterocyclic carbene catalytic system in the reaction of β‐oxo sulfones with unsaturated aldehydes. In addition, the influence of the catalysts on the diastereoselectivity of the final product was studied by 1 H NMR spectroscopy.
Keywords
Chemistry
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