Postoperative delirium in old patients with femoral neck fracture: a randomized intervention study
Aging Clinical and Experimental ResearchPublished 1 June 2007Open access
Maria Lundström, Birgitta Olofsson, Michael Stenvall, Stig Karlsson, Lars Nyberg, Undis Englund
Citations279
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TL;DR
Patients with postoperativeDelirium can be successfully treated, resulting in fewer days of delirium, fewer other complications, and shorter length of hospitalization.
Abstract
Patients with postoperative delirium can be successfully treated, resulting in fewer days of delirium, fewer other complications, and shorter length of hospitalization.
Keywords
MedicineNeuroscience
Encyclopedia of Social WorkDiagnostic and Statistical Manual of Mental Disorders
109,983 Citations2013Janet B. W. Williams, Michael B. First
Journal of Psychiatric Research“Mini-mental state”
86,858 Citations1975Marshal F. Folstein, Susan E. Folstein +1 more
A simplified, scored form of the cognitive mental status examination, the “Mini-Mental State” (MMS) which includes eleven questions, requires only 5-10 min to administer, and is therefore practical to use serially and routinely.
SpringerReferenceDiagnostic and Statistical Manual of Mental Disorders
20,887 Citations2012
This chapter provides a brief critical overview of the Diagnostic and Statistical Manual of Mental Disorders.
Journal of Psychiatric ResearchDevelopment and validation of a geriatric depression screening scale: A preliminary report
15,041 Citations1982Jerome A. Yesavage, T. L. Brink +5 more
The GDS represents a reliable and valid self-rating depression screening scale for elderly populations and was significantly better correlated with RDC symptoms than was the SDS.
PubMedSTUDIES OF ILLNESS IN THE AGED. THE INDEX OF ADL: A STANDARDIZED MEASURE OF BIOLOGICAL AND PSYCHOSOCIAL FUNCTION.
12,208 Citations1963Sidney Katz, A B FORD +3 more
Clinical Gerontologist9/Geriatric Depression Scale (GDS)
7,192 Citations1986Jerome A. Yesavage, Javaid I. Sheikh
New England Journal of MedicineA Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients
2,849 Citations1999Sharon K. Inouye, Sidney T. Bogardus +5 more
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Journal of the American Geriatrics SocietyReducing Delirium After Hip Fracture: A Randomized Trial
1,378 Citations2001Edward R. Marcantonio, Jonathan M. Flacker +2 more
The aim of this study was to establish an experimental procedure that can be used as a guide for the design of future studies on randomized trials of this type.
Journal of Bone and Joint Surgery - British VolumeLOW-ANGLE FIXATION IN FRACTURES OF THE FEMORAL NECK
978 Citations1961R. S. Garden
It is suggested that those subcapital separations which follow trivial injury may originate as stress fractures accompanying the process of bone remodelling in the aged, and that many of these fractures may remain unrecognised and heal spontaneously.
Journal of the American Geriatrics SocietyDelirium Is Independently Associated with Poor Functional Recovery After Hip Fracture
687 Citations2000Edward R. Marcantonio, Jonathan M. Flacker +2 more
The role of delirium in the natural history of functional recovery after hip fracture surgery, independent of prefracture status, is evaluated.
ScienceGlucocorticoids Potentiate Ischemic Injury to Neurons: Therapeutic Implications
679 Citations1985Robert M. Sapolsky, William A. Pulsinelli
It is shown that ischemic injury to neurons in rat brain is also potentiated by exposure to high physiological titers of glucocorticoids and is attenuated by adrenalectomy.
Journal of the American Geriatrics SocietyEfficacy of a Comprehensive Geriatric Intervention in Older Patients Hospitalized for Hip Fracture: A Randomized, Controlled Trial
570 Citations2005Maite Vidán, José Antonio Serra Rexach +3 more
Whether an early multidisciplinary geriatric intervention in elderly patients with hip fracture reduced length of stay, morbidity, and mortality and improved functional evolution is evaluated.
Journal of the American Geriatrics SocietyAcute Confusional States in Elderly Patients Treated for Femoral Neck Fracture
479 Citations1988Yngve Gustafson, Diana Berggren +5 more
The aims of this study were to estimate the incidence of acute confusional state, its predisposing factors and consequences in 111 consecutive patients operated for fractured neck of the femur, and the predicting factors were old age and dementia.
Journal of the American Geriatrics SocietyA Multifactorial Intervention Program Reduces the Duration of Delirium, Length of Hospitalization, and Mortality in Delirious Patients
387 Citations2005Maria Lundström, Agneta Edlund +4 more
Journal of the American Geriatrics SocietyA Nurse‐Led Interdisciplinary Intervention Program for Delirium in Elderly Hip‐Fracture Patients
371 Citations2001Koen Milisen, Marquis D. Foreman +8 more
International Journal of Geriatric PsychiatryAccuracy of the 15‐item geriatric depression scale (GDS‐15) in a community sample of the oldest old
368 Citations2002Anton J.M. de Craen, Thea J. Heeren +1 more
Cognitive impairment is common in the oldest old, and this might influence the and specificity of the 15‐item Geriatric Depression Scale (GDS‐15), a screening instrument for depression.
Survey of AnesthesiologyPostoperative Confusion After Anesthesia in Elderly Patients with Femoral Neck Fractures
280 Citations1987Diana Berggren, Yngve Gustafson +5 more
It is concluded that anticholinergic medication and a history of mental depression are predominant risk factors for development of postoperative confusion and in this respect are more important than the anesthetic technique.
Journal of the American Geriatrics SocietyA Geriatric‐Anesthesiologic Program To Reduce Acute Confusional States in Elderly Patients Treated for Femoral Neck Fractures
271 Citations1991Yngve Gustafson, Benny Brännström +7 more
It can be concluded that the intervention program reduced the incidence, severity, and duration of ACS which resulted in a shortened orthopedic ward stay.
Anesthesia & AnalgesiaPostoperative Confusion after Anesthesia in Elderly Patients with Femoral Neck Fractures
262 Citations1987Diana Berggren, Yngve Gustafson +5 more
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235 Citations2003Maria Lundström, Agneta Edlund +3 more
Whether delirium in older patients with femoral neck fractures is associated with an increased risk of developing dementia and a higher mortality rate is investigated.
The Journals of Gerontology Series ANeural Mechanisms of Delirium: Current Hypotheses and Evolving Concepts
214 Citations1999Jonathan M. Flacker, Lewis A. Lipsitz
Delirium is a syndrome that may occur as the result of multiple complex interacting neurotransmitter systems and pathologic processes and its mechanisms may differ in various clinical settings.
Journal of the American Geriatrics SocietyUnderdiagnosis and Poor Documentation of Acute Confusional States in Elderly Hip Fracture Patients
197 Citations1991Yngve Gustafson, Benny Brännström +3 more
Research in Nursing & HealthReducing acute confusional states in elderly patients with hip fractures
155 Citations1985Margaret A. Williams, Emily B. Campbell +3 more
The most effective interventions appeared to be those that provided orientation and clarification, corrected sensory deficit, and increased continuity of care.
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GerontologyAcute Confusional States in Patients Undergoing Hip Surgery
111 Citations1999Gill Sörensen Duppils, Karin Wikblad
Investigating the onset of ACS during hospital stay and isolating possible predisposing, facilitating and precipitating factors found older age, cognitive impairment and pre-existing cerebrovascular or other brain diseases to be factors associated with ACS.
International Journal of Geriatric PsychiatryA comparison between three psychogeriatric rating scales
111 Citations1993Elmo Jensen, Ove Dehlin +1 more
The OBS scale contributes unique clinical information and is a valid instrument for assessment of dementia symptoms and the correlations between OBS, GBS and MMSE were high, showing that the concurrent validity is good.
PsychoneuroendocrinologyBeta-endorphin, cortisol and postoperative delirium: a preliminary report
110 Citations1985Tracy K. McIntosh
A transient delirium occurred at some time during a 48 to 72 hr postoperative period in patients recovering from elective surgery in an intensive care unit, and a disruption in circadian rhythms of the endogenous opiate/hypothalamic-pituitary-adrenal axis may represent an important component of post-operative psychological changes that are frequently observed.
Scandinavian Journal of Caring SciencesReorganization of Nursing and Medical Care to Reduce the Incidence of Postoperative Delirium and Improve Rehabilitation Outcome in Elderly Patients Treated for Femoral Neck Fractures
84 Citations1999Maria Lundström, Agneta Edlund +2 more
It can be concluded that the intervention programme reduced the incidence and duration of delirium and improved functional outcome for elderly patients treated for femoral neck fractures.
Scandinavian Cardiovascular JournalDelirium after Coronary Bypass Surgery Evaluated by the Organic Brain Syndrome Protocol
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Hallucinations were common in both delirious and non-delirious patients and a major finding was a 58% frequency of hallucinations and illusions among patients with delirium, and a similar rate among those withoutDelirium.
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A dexamethasone suppression test in 16 consecutive patients without depression or dementia admitted to an acute-care geriatric unit with a clinical diagnosis of lower respiratory tract infection suggested that such patients may be at increased risk for developing delirium during acute illness.
Dementia and Geriatric Cognitive DisordersActivity in the Hypothalamic-Pituitary- Adrenal Axis and Delirium
68 Citations1999Tommy Olsson
In experimental models, the hippocampal formation is of prime importance for normal HPA axis shut-off, and a close interaction between neurotransmittors is present and possibly relevant for the development of delirium in elderly patients with stroke and neurodegenerative brain diseases.
PubMedGeriatric work-up in the Nordic countries. The Nordic approach to comprehensive geriatric assessment.
54 Citations1996Olav Sletvold, R. S. Tilvis +6 more
A group established by the Nordic professors of geriatrics has developed a position document presenting a shared and updated review of geriatric work-up as a way of comprehensive geriatric assessment in the Nordic countries, presented with success factors and barriers.
International Journal of Geriatric PsychiatryThe Organic Brain Syndrome (OBS) scale: a systematic review
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PubMed[Geriatric rehabilitation as an integral part of geriatric medicine in the nordic countries.].
11 Citations2002Ársæll Jónsson, Pálmi V. Jónsson +8 more
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