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Effect of hemicholinium-3 on slow wave and paradoxical sleep of cat

European Journal of PharmacologyPublished 1 August 1970
Jagadish P. Hazra
Citations39
SJR quartileQ1
SJR score1.20
SNIP0.98

TL;DR

It is concluded that ACh activity maintains the states of vigilance and, more so, the phenomenon of dreaming in cats.

Abstract

The role of brain ACh on sleep, wakefulness and dreams in cats was investigated. Graded doses of HC-3 were injected into the 4th ventricle and their effects were studied with EEG recordings from chronic cats. HC-3 facilitated SWS in dose dependent fashion; however, PS was virtually abolished with as little as 1 μg of HC-3. It is concluded that ACh activity maintains the states of vigilance and, more so, the phenomenon of dreaming.

Keywords

Neuroscience