Effect of antidepressant drug counselling and information leaflets on adherence to drug treatment in primary care: randomised controlled trial
BMJPublished 4 September 1999Open access
Robert Peveler, C. George Priya Doss, Ann Louise Kinmonth, Michael J. Campbell, Christopher Thompson
Citations259
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TL;DR
A brief psychosocial intervention delivered by a nurse greatly improved adherence and clinical benefit was apparent only in patients with major depressive episodes on higher doses of drugs.
Abstract
Counselling about drug treatment significantly improved adherence, but clinical benefit was seen only in patients with major depressive disorder receiving doses >/=75 mg. Further research is required to evaluate the effect of this approach in combination with appropriate targeting of treatment and advice about dosage.
Keywords
Medicine
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