login

Correlation of anxiety and related symptoms with cerebrospinal fluid 5-hydroxyindoleacetic acid in depressed women

Journal of Neural TransmissionPublished 1 June 1977
Csaba M. Bánki
Citations63
SJR quartileQ1
SJR score1.11
SNIP1.13

TL;DR

Values were found to be lower in depression as compared to controls, but they did not correlate with the severity of the clinical picture, while anxiety, insomnia and drug response however showed significant correlation with pretreatment 5-HIAA level.

Abstract

Cerebrospinal fluid 5-hydroxyindoleacetic acid levels were determined in 31 women with unipolar involutional depression using the probenecid technique. Values were found to be lower in depression as compared to controls, but they did not correlate with the severity of the clinical picture. Anxiety, insomnia and drug response however showed significant correlation with pretreatment 5-HIAA level. Some possible interpretations are discussed.

Keywords

MedicineNeuroscience