Effect of Ethinyl-Oestradiol on Some Neurohypophysial Active Compounds in the Rat
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TL;DR
Radio-immunoassay of neurophysin, using an antiserum directed against an antigenic fragment common to various neurophysins, has enabled it to be shown that this hypo-thalamo-neurohypophysial carrier of active hormones such as vasopressin or antidiuretic hormone and oxytocin is released concomitantly with them in various animal species both in vitro and in vivo.
Abstract
THE radio-immunoassay (RIA) of neurophysin, using an antiserum directed against an antigenic fragment common to various neurophysins, has enabled us to show that this hypo-thalamo-neurohypophysial carrier of active hormones such as vasopressin or antidiuretic hormone (ADH) and oxytocin (Oxy) is released concomitantly with them in various animal species both in vitro1–2; and in vivo. It appeared therefore that RIA of neurophysin could be a useful tool to explore neurohypophysial activity directly.