Anti-depressive treatment in Parkinson's disease A CONTROLLED TRIAL OF THE EFFECT OF NORTRIPTYLINE IN PATIENTS WITH PARKINSON'S DISEASE TREATED WITH L-DOPA
Acta Neurologica ScandinavicaPublished 29 January 2009
Jack Andersen, E. Aabro, N. C. Gulmann, A. Hjelmsted, Holger Ejgil Pedersen
Citations218
SJR quartileQ1
SJR score0.95
SNIP1.04
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TL;DR
The authors suggest the depression in Parkinson's disease to be of both reactive and endogenous origins.
Abstract
Nineteen patients with L-DOPA treated parkinsonism involving depressive symptoms, the therapeutic effect of nortriptyline was compared to placebo in a controlled trial. The depressive and neurological symptoms were evaluated by rating scales. Nortriptyline had a clinical significant effect with regard to the depressive symptoms, whereas the neurological parameters were unchanged. The authors suggest the depression in Parkinson's disease to be of both reactive and endogenous origins.
Keywords
Medicine
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