Efficacy and Safety of Sibutramine in Obese White and African American Patients With Hypertension
Archives of Internal MedicinePublished 24 July 2000
F. Gilbert McMahon, Ken Fujioka, Bramah N. Singh, Carl M. Mendel, Everton Rowe, K. V. I. Rolston
Citations247
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TL;DR
In obese patients with controlled hypertension, sibutramine was an effective and well-tolerated treatment for weight loss and maintenance and was associated with significant improvements in serum levels of triglycerides, HDL-C, glucose, and uric acid.
Abstract
In obese patients with controlled hypertension, sibutramine was an effective and well-tolerated treatment for weight loss and maintenance. Sibutramine-induced weight loss resulted in improvements in serum levels of triglycerides, HDL-C, uric acid, and glucose, and in waist circumference and quality-of-life measures. Blood pressure and heart rate increased by a small amount. Efficacy and safety profiles for sibutramine among African American and white obese patients with controlled hypertension were similar.
Keywords
PsychologyMedicine
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