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Investigations of the Occurrence of Gentamicin-Resistant <i>Staphylococcus aureus</i>

Antimicrobial Agents and ChemotherapyPublished 1 February 1979Open access
Frederick J. Buckwold, W L Albritton, Allan Ronald, Joy Lertzman, Ruby Henriksen
Citations17
SJR quartileQ1
SJR score1.43
SNIP1.10
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TL;DR

During the 19-month period from June 1976 to December 1977, 90 patients became colonized or infected with gentamicin-resistant Staphylococcus aureus (GRS).

Abstract

During the 19-month period from June 1976 to December 1977, 90 patients became colonized or infected with gentamicin-resistant Staphylococcus aureus (GRS). Of 63 adults, 56 had hospital-acquired GRS, whereas only 9 of 27 children had hospital-acquired GRS (P /= 8 mug/ml) and almost all were tobramycin resistant (MIC >/= 8 mug/ml). Although the MIC distribution between gentamicin disk-susceptible and -resistant strains was significantly different, MIC's for 90% of gentamicin disk-resistant strains were </=8 mug of amikacin per ml, and MIC's for 92% of the strains were </=4 mug of netilmicin per ml.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology