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CLUSTAL V: improved software for multiple sequence alignment

Computer applications in the biosciencesPublished 1 January 1992Open access
Desmond G. Higgins, Alan J. Bleasby, Rainer Fuchs
Citations2,396
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TL;DR

The CLUSTAL package of multiple sequence alignment programs has been completely rewritten and many new features added, the main new features are the ability to store and reuse old alignments and to calculate phylogenetic trees after alignment.

Abstract

The CLUSTAL package of multiple sequence alignment programs has been completely rewritten and many new features added. The new software is a single program called CLUSTAL V, which is written in C and can be used on any machine with a standard C compiler. The main new features are the ability to store and reuse old alignments and the ability to calculate phylogenetic trees after alignment. The program is simple to use, completely menu driven and on-line help is provided.

Keywords

Biochemistry, Genetics and Molecular Biology