Prognostic Value of a Treadmill Exercise Score in Outpatients with Suspected Coronary Artery Disease
New England Journal of MedicinePublished 19 September 1991Open access
Daniel B. Mark, Linda K. Shaw, Frank E. Harrell, Mark A. Hlatky, Kerry L. Lee, James R. Bengtson
Citations829
SJR quartileQ1
SJR score19.08
SNIP13.47
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
The treadmill score is a useful and valid tool that can help clinicians determine prognosis and decide whether to refer outpatients with suspected coronary disease for cardiac catheterization, and was a better predictor of outcome than the clinical assessment.
Abstract
The treadmill score is a useful and valid tool that can help clinicians determine prognosis and decide whether to refer outpatients with suspected coronary disease for cardiac catheterization. In this study, it was a better predictor of outcome than the clinical assessment.
Keywords
Medicine
Journal of the Royal Statistical Society Series B (Statistical Methodology)Regression Models and Life-Tables
39,259 Citations1972D. R. Cox
RadiologyThe meaning and use of the area under a receiver operating characteristic (ROC) curve.
21,812 Citations1982J A Hanley, Barbara J. McNeil
A representation and interpretation of the area under a receiver operating characteristic (ROC) curve obtained by the "rating" method, or by mathematical predictions based on patient characteristics, is presented and it is shown that in such a setting the area represents the probability that a randomly chosen diseased subject is (correctly) rated or ranked with greater suspicion than a random chosen non-diseased subject.
Journal of the American Statistical AssociationNonparametric Estimation from Incomplete Observations
7,727 Citations1958Edward L. Kaplan, Paul Meier
Statistics in MedicineRegression modelling strategies for improved prognostic prediction
1,836 Citations1984Frank E. Harrell, Kerry L. Lee +3 more
A general index of predictive discrimination is used to measure the ability of a model developed on training samples of varying sizes to predict survival in an independent test sample of patients suspected of having coronary artery disease.
Annals of Internal MedicineExercise Treadmill Score for Predicting Prognosis in Coronary Artery Disease
663 Citations1987Daniel B. Mark, MARK A. HLATKY +4 more
The treadmill score was useful for stratifying prognosis in patients with suspected coronary artery disease who were referred to us for catheterization, and may provide a useful adjunct to clinical decision making in the larger population of patients being evaluated for chest pain.
CirculationThe role of the exercise test in the evaluation of patients for ischemic heart disease.
499 Citations1978J F McNeer, James R. Margolis +8 more
The exercise test is a nonin invasive, reproducible method to assess the presence and extent of anatomic disease and the prognosis when significant disease has been defined and should be used in conjunction with other noninvasive tests to determine optimal management in patients evaluated for ischemic heart disease.
CirculationPredictive implications of stress testing. Follow-up of 2700 subjects after maximum treadmill stress testing.
461 Citations1975Myrvin Ellestad, Maolin Wan
Those with chronotropic incompetence had a high incidence of coronary events even though the ECG response to exercise was normal, and a myocardial infarction previous to the test increased the incidence of events in both positive and negative responders.
Journal of the American College of CardiologyPrognostic importance of a clinical profile and exercise test in medically treated patients with coronary artery disease
387 Citations1984Donald A. Weiner, Thomas J. Ryan +6 more
In patients with defined coronary pathoanatomy, clinical and exercise variables primarily relating to the functional state of the left ventricle are helpful in assessing prognosis.
The American Journal of MedicineEstimating the likelihood of significant coronary artery disease
356 Citations1983David B. Pryor, Frank E. Harrell +3 more
Clinical characteristics examined in 3,627 consecutive, symptomatic patients referred for cardiac catheterization between 1969 and 1979 found to be important for estimating the likelihood a patient had significant coronary artery disease accurately estimated the likelihood of disease.
The LancetAssessment of priority for coronary revascularisation procedures
157 Citations1990C. David Naylor, R.S Baigne +2 more
To develop guidelines for ranking the urgency with which patients with angiographically proven coronary disease need revascularisation procedures, factors that a panel of cardiac specialists agreed were likely to affect urgency were incorporated into 438 fictitious case-histories.
Journal of the American College of CardiologyEnhanced risk assessment for primary coronary heart disease events by maximal exercise testing: 10 years' experience of Seattle heart watch
147 Citations1983Robert A. Bruce, Kenneth F. Hossack +2 more
Observation of the exercise predictors in the absence of conventional risk factors increased the risk much less, suggesting that the use of maximal exercise testing for risk assessment in those with no clinical manifestations of disease might be limited to persons with one or more conventional risk Factors.
American Heart JournalPrognostic assessment of patients with coronary artery disease by exercise testing
67 Citations1983Donald A. Weiner, Carolyn H. McCabe +1 more
Combinations of clinical and exercise variables to distinguish high- and low-risk subgroups of patients with similar coronary anatomy is useful in predicting cardiac mortality.
JAMAThe evolution of medical and surgical therapy for coronary artery disease. A 15-year perspective
45 Citations1989Robert M. Califf
Archives of Internal MedicineA new information system for medical practice
25 Citations1975R. A. Rosati
Disease-a-MonthThe prognostic value of the exercise test exercise test
12 Citations1988Victor F. Froelicher, G. Duarte
It is concluded that silent ischemia induced by exercise testing in apparently healthy men is not as predictive of a poor outcome as once thought, and the use of the exercise test for screening is even more misleading than previously appreciated because of the higher rate of false positive results.