Thy‐1 determinants are present on many murine hematopoietic Cells other than T Cells
European Journal of ImmunologyPublished 1 January 1982
Ross S. Basch, Joan W. Berman
Citations119
SJR quartileQ1
SJR score1.86
SNIP0.90
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TL;DR
The development of a highly amplified immunofluorescence assay and the availability of monoclonal anti‐Thy‐1 antibodies have provided the methodology to reexamine the presence of Thy‐1 antigen on murine lymphohematopoietic cells and found it is present on a significant number of mouse bone marrow cells.
Abstract
The development of a highly amplified immunofluorescence assay and the availability of monoclonal anti-Thy-1 antibodies have provided the methodology to reexamine the presence of Thy-1 antigen on murine lymphohematopoietic cells. The representation of this antigen is not, as previously believed, restricted to the T cell compartment of these cells. It is present on a significant number of mouse bone marrow cells (25-30%), including, as in the rat, multipotential stem cells, prothymocytes and some B cell precursors. Eosinophils and some immature myeloid cells are also antigen-positive.
Keywords
Immunology and MicrobiologyAgricultural and Biological Sciences
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