Quantitative stereology of synapses: A critical investigation
Brain ResearchPublished 1 August 1973
Gijs F.J.M. Vrensen, D. De Groot
Citations51
SJR quartileQ2
SJR score0.85
SNIP0.72
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TL;DR
The quantitative characterization of synapses in O s O 4 - and ethanolic phosphotungstic acid acid acid (E-PTA)-treated nervous tissue is reinvestigated making use of recent progress an quantitative stereology and reveals that the E- PTA-stained synaptic junctions are qualitatively and quantitatively equivalent to the membrane thickenings of the O sO 4 -treated synaptic contact zones.
Abstract
The quantitative characterization of synapses in O sO4- and ethanolic phosphotungstic acid acid (E-PTA)-treated nervous tissue is reinvestigated making use of recent progress an quantitative stereology. The surface area of synaptic junctions per volume and the mean length of the synaptic contact zones are introduced as parameters. It reveals that the E-PTA-stained synaptic junctions are qualitatively and quantitatively equivalent to the membrane thickenings of the OsO4-treated synaptic contact zones. The relevance of quantitative synaptology is discussed.
Keywords
Computer ScienceBiochemistry, Genetics and Molecular BiologyEngineering
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