Behaviour of a Synthetic Polypeptide analogous to Protein Denaturation
NaturePublished 1 December 1952
A. Elliott
Citations29
SJR quartileQ1
SJR score18.29
SNIP10.16
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TL;DR
Observations made recently suggest a considerable resemblance, in certain respects, between poly DL-alanine and the soluble form of silk obtained from solution in cupriethylene diamine or lithium bromide solution.
Abstract
SOME observations made recently in this laboratory suggest a considerable resemblance, in certain respects, between poly DL-alanine and the soluble form of silk obtained from solution in cupriethylene diamine or lithium bromide solution1,2.
Keywords
Materials Science
Biochemical JournalThe X-ray interpretation of denaturation and the structure of the seed globulins
380 Citations1935W. T. ASTBURY, Sylvia Dickinson +1 more
It was found that heat-denaturation of the albumins, for instance, merely makes the X-ray photograph more like that of a random arrangement of fibres of/-keratin (stretched hair, horn, etc.; cf. Plate V, Figs. 1 and 3).
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It is shown that the polypeptides can undergo an α→β transformation similar to that encountered in the fibrous α proteins, and a mechanism for this transformation is suggested.
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57 Citations1947DenisR Coleman, F. O. Howitt
Proceedings of the Royal Society of London A Mathematical and Physical SciencesThe structure of synthetic polypeptides III. The molecular configurations and physical properties of some regenerated synthetic polypeptides
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