Cloning of the <i>Arabidopsis</i> Clock Gene <i>TOC1</i> , an Autoregulatory Response Regulator Homolog
SciencePublished 4 August 2000
Carl A. Strayer, Tokitaka Oyama, Thomas F. Schultz, Ramanujam Raman, David E. Somers, Paloma Más
Citations853
SJR quartileQ1
SJR score10.42
SNIP6.62
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TL;DR
The toc1 mutation causes shortened circadian rhythms in light-grown Arabidopsis plants and it is shown that TOC1 controls photoperiodic flowering response through clock function.
Abstract
The toc1 mutation causes shortened circadian rhythms in light-grown Arabidopsis plants. Here, we report the same toc1 effect in the absence of light input to the clock. We also show that TOC1 controls photoperiodic flowering response through clock function. The TOC1 gene was isolated and found to encode a nuclear protein containing an atypical response regulator receiver domain and two motifs that suggest a role in transcriptional regulation: a basic motif conserved within the CONSTANS family of transcription factors and an acidic domain. TOC1 is itself circadianly regulated and participates in a feedback loop to control its own expression.
Keywords
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