Regulators and effectors of the ARF GTPases
Current Opinion in Cell BiologyPublished 1 August 2000
Julie G. Donaldson, Catherine Jackson
Citations390
SJR quartileQ1
SJR score2.78
SNIP1.19
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TL;DR
Significant progress has been made over the past year, with the identification of a surprisingly large family of novel ARF GTPase-activating proteins and two new classes of effectors.
Abstract
The small G proteins of the ARF family are key regulators of membrane dynamics. Many functions of ARF proteins in cells are being revealed by studies of their regulators and effectors. Significant progress has been made over the past year, with the identification of a surprisingly large family of novel ARF GTPase-activating proteins. In addition, two new classes of effectors, the PIP kinases and a novel family of monomeric coat-like proteins have been discovered.
Keywords
Biochemistry, Genetics and Molecular Biology
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