Estrogen and Neural Plasticity
Current Directions in Psychological SciencePublished 1 October 2000
Michael R. Foy, Victor W. Henderson, Theodore W. Berger, Richard F. Thompson
Citations44
SJR quartileQ1
SJR score3.21
SNIP3.16
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TL;DR
Mechanisms of action of estrogen on neurons and synaptic plasticity, and how they might protect against the cognitive impairments of old age are considered.
Abstract
Converging clinical evidence suggests that postmenopausal estrogen therapy in women is associated with improved cognition and a reduced incidence of Alzheimer's disease. In experimental work, investigators have found estrogen to promote changes in synaptic plasticity within the nervous system. In this article, we review both the clinical and the experimental literature, and consider mechanisms of action of estrogen on neurons and synaptic plasticity, and how they might protect against the cognitive impairments of old age.
Keywords
MedicineNeuroscienceBiochemistry, Genetics and Molecular Biology
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