Panic disorder: Genetic considerations
Journal of Psychiatric ResearchPublished 1 January 1990
Raymond R. Crowe
Citations23
SJR quartileQ1
SJR score1.49
SNIP1.15
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TL;DR
A preliminary linkage analysis of panic disorder found suggestive but inconclusive evidence of linkage to the alpha-haptoglobin locus on chromosome 16q22.
Abstract
Panic disorder is a common illness that can have serious consequences, including increased long-term mortality. Family and twin studies suggest that it is a genetic disorder and transmission patterns within families are compatible with a hypothesis of a disease gene predisposing to the condition. Recently, it has become possible to locate disease genes causing familial disorders through linkage analysis. A preliminary linkage analysis of panic disorder at the University of Iowa found suggestive but inconclusive evidence of linkage to the alpha-haptoglobin locus on chromosome 16q22. Future strategies for identifying disease genes in anxiety disorders are described.
Keywords
PsychologyMedicineBiochemistry, Genetics and Molecular Biology
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