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Human fat cell sizing—a quick, simple method

Journal of Lipid ResearchPublished 1 March 1976Open access
Margaret Ashwell, Pauline Priest, M Bondoux, C Sowter, Craig McPherson
Citations58
SJR quartileQ1
SJR score1.66
SNIP1.20
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TL;DR

Method II has several advantages over Method I and it is proposed that it is a suitable method for sizing cells when a quick method with a permanent record is required.

Abstract

Two methods were used to determine the mean cell diameters of 37 samples of human adipose tissue, obtained by open or needle biopsy. Method I was the sizing of cells in cell suspensions and Method II was a quick, simple method of sizing cells from fixed sections. The agreement between the two methods was good (r = 0.93, P = less than 0.001). The results using Method II were slightly lower than those using Method I, and a correction factor is suggested. Method II has several advantages over Method I and we propose that it is a suitable method for sizing cells when a quick method with a permanent record is required.

Keywords

Medicine