[Detection of antibodies to HIV virus in saliva by express-tests in Uzbekistan].
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TL;DR
The main quality parameters of express-test for the detection of anti-HIV in saliva were evaluated and the test is appropriate for epidemiological investigations and HIV epidemiological supervision but it cannot be recommended for the blood transfusion service.
Abstract
Saliva tests, when used in screening for antibodies to HIV virus (anti-HIV), makes testing safer, easy-to-fulfill (even outside clinic) and acceptable for a majority of examinees. The main quality parameters of express-test for the detection of anti-HIV in saliva were evaluated for the purpose of using the related approach in the HIV epidemiological supervision. Saliva samples and sera of 81 HIV-infected patients and of 99 presumably non-infected persons were investigated by the "OraQuick" express-test. The data obtained were compared with the results of ELISA-based serum testing. The sensitivity of "OraQuick" made 95% and its specificity was 100%. The test is appropriate for epidemiological investigations and HIV epidemiological supervision but it cannot be recommended for the blood transfusion service.