THE NORMAL OCCURRENCE OF OCTOPAMINE IN NEURAL TISSUES OF THE <i>OCTOPUS</i> AND OTHER CEPHALOPODS
Journal of NeurochemistryPublished 1 February 1974
A. V. Juorio, Perry B. Molinoff
Citations66
SJR quartileQ1
SJR score1.50
SNIP1.02
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Findings suggest that octopamine may be involved in neuronal function in cephalopods.
Abstract
Abstract— An enzymatic assay was used to measure the concentration of octopamine in tissue of cephalopods. The concentration of octopamine varied over a wide range in neural tissues of Octopi and other cephalopods. The administration of reserpine caused a fall in the concentration of octopamine while monoamine oxidase inhibition caused the concentration to rise. After density gradient centrifugation octopamine was found in the same regions of the gradients as were dopamine and noradrenaline. These findings suggest that octopamine may be involved in neuronal function in cephalopods.
Keywords
Agricultural and Biological SciencesNeuroscience
The Journal of Cell BiologyTHE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY
25,027 Citations1963Edward S. Reynolds
The stain reported here differs from previous alkaline lead stains in that the chelating agent, citrate, is in sufficient excess to sequester all lead present, and is less likely to contaminate sections.
Journal of Pharmacology and Experimental TherapeuticsIDENTIFICATION AND ASSAY OF SEROTONIN IN BRAIN
864 Citations1956Donald F. Bogdanski, A. Pletscher +2 more
With this method serotonin has been shown to be a normal constituent of brain and may be applied to the measurement of serotonin in other tissues.
ScienceRegeneration in Crustacean Motoneurons: Evidence for Axonal Fusion
221 Citations1967Ronald R. Hoy, George D. Bittner +1 more
ScienceOctopamine-Sensitive Adenylate Cyclase: Evidence for a Biological Role of Octopamine in Nervous Tissue
216 Citations1973James A. Nathanson, Paul Greengard
An adenylate cyclase that is activated specifically by very low concentrations of octopamine has been identified both in homogenates and in intact cells of the thoracic ganglia of an insect nervous system, raising the possibility of a role ofOctopamine-sensitive adenYLate cyclases in the physiology of synaptic transmission.
British Journal of Pharmacology and ChemotherapyTHE ESTIMATION OF SMALL QUANTITIES OF 3,4‐DIHYDROXYPHENYLETHYLAMINE IN TISSUES
198 Citations1965R. Laverty, D.F. Sharman
Of the chemical methods applicable to the estimation of dopamine only those involving the formation of a fluorescent derivative are likely to be sensitive enough to estimate the small amounts of dopamine occurring in some tissues.
PubMedAn enzymatic assay for octopamine and other beta-hydroxylated phenylethylamines.
171 Citations1969Perry B. Molinoff, Lewis Landsberg +1 more
Minor modifications of the assay procedure make it suitable for the measurement of Phenylethanolamine, and this compound has been measured in rat organs after the administration of phenylethylamine.
Journal of NeurochemistryDISTRIBUTION AND TURNOVER OF OCTOPAMINE IN TISSUES
120 Citations1972Perry B. Molinoff, J Axelrod
The physiological role of octopamine has not been established but it appears likely that it is a cotransmitter together with norepinephrine in the peripheral sympathetic nervous system.
Philosophical transactions of the Royal Society of London. Series B, Biological sciencesThe optic lobes of <i>Octopus vulgaris</i>
116 Citations1962John Zachary Young
It is suggested that the variety of shapes of the dendritic trees within the optic lobes provides the elements of the coding system by which visual input is classified.
ScienceOctopamine: Normal Occurrence in Sympathetic Nerves of Rats
111 Citations1969Perry B. Molinoff, Julius Axelrod
Octopamine has been identified in several organs of normal rats by means of a sensitive enzymatic assay and is localized within the sympathetic nerve endings.
The Journal of PhysiologyCatecholamines and 5‐hydroxytryptamine in nervous tissue of cephalopods
99 Citations1971A. V. Juorio
Catecholamines and 5‐hydroxytryptamine were measured fluorimetrically in nervous tissue of cephalopod molluscs and the results confirmed the role of E.1.
Journal of NeurochemistryCHOLINERGIC NERVE ENDINGS IN OCTOPUS BRAIN
66 Citations1968Ernst Florey, J. Winesdorfer
Optic lobes of the brains of Octopus dofleini werehomogenized hasaline–sucrose medium and subjected to differential and density gradient centrifugation, and a large portion of ACh could be recovered in subfractions that contained predominantly nerve endings.
Archives of Internal MedicineCLINICAL EVALUATION OF 4-HYDROXYCOUMARIN ANTICOAGULANT NO. 63
62 Citations1951Royal Rotter
In dogs and in human beings this anticoagulant was a strong competitor, if not an agent superior, to bishydroxycoumarin and in work done by Scheel2 in the mouse, rat, rabbit, and dog, attention was given not only to activity per se, but also to the time and site of appearance of visible hemorrhage and the survival time resulting from continued administration of various coumarin antICOagulants.
Comparative and General PharmacologyMonoamines and their metabolism in some molluscs
58 Citations1972A. V. Juorio, Stephanie Killick
The concentrations of noradrenaline, dopamine, and 5-hydroxytryptamine found in the optic lobes of the octopods Octopus vulgaris, Octopus macropus, and Eledone moschata were consistently higher than the amine concentrations in the fibre-based concentrations of the decapods Loligo vulgaris and Sepia officianalis.
Cellular and Molecular Life SciencesThe presence of octopamine in the brain ofHelix aspersa and its action on specific snail neurones
52 Citations1972R.J. Walker, Andrew G. Ramage +1 more
L'octopamine est présente dans le tissue nerveus l'escargot,Helix aspersa, un effet fortement inhibitoire sur certains neurones sont aussi sensibles à la dopamine et à the noradrénaline.
Acta Physiologica ScandinavicaPresence of Catechol Amines in Visceral Organs of‘ Fish and Invertebrates.
48 Citations1953U. S. von Euler
The Journal of PhysiologyObservations on amine oxidase in cephalopods
44 Citations1952H. Blaschko, Joyce Hawkins
NatureTeacher Attitudes to Projects in A-Level Engineering Science
37 Citations1972Diana Hiles, John S. Heywood
Comparative Biochemistry and Physiology Part A PhysiologyThe distribution of monoamines and some of their acid metabolites in the posterior salivary glands and viscera of some cephalopods
31 Citations1973A. V. Juorio, Stephanie Killick
The crop and oesophagus were the only regions of the alimentary tract of octopod molluscs found to contain monoamines and the administration of reserpine led to a marked reduction in the concentration of dopamine and noradrenaline in the crop-oesophagus and the posterior salivary glands.
The Japanese Journal of PharmacologyPHARMACOLOGICAL ACTION OF OCTOPAMINE WITH SPECIAL REFERENCE TO BIOCHEMICAL CONVERSION TO NORADRENALINE
15 Citations1968Motohatsu Fujiwara, Keisuke Hattori +3 more
In the present experiments it was attempted to correlate sympathomimetic effects of octopamine with the endogenous noradrenaline by means of pharmacological, biochemical and histochemical techniques.