login

The Genetic Epidemiology of Schizophrenia in a Finnish Twin Cohort

Archives of General PsychiatryPublished 1 January 1998
Tyrone D. Cannon, Jaakko Kaprio, Jouko Lönnqvist, Matti Huttunen, Markku Koskenvuo
Citations454

TL;DR

In a population-based twin study of schizophrenia, heritability was estimated at 83%, with the remaining variance in liability attributed to environmental factors not shared in common among co-twins.

Abstract

In a population-based twin study of schizophrenia, heritability was estimated at 83%, with the remaining variance in liability attributed to environmental factors not shared in common among co-twins. Despite the notable limitation of using diagnoses ascertained through treatment contacts, the heritability estimate in this study is almost identical to those reported in recent studies of index pairs using standardized applications of DSM-III or later criteria.

Keywords

PsychologyMedicineBiochemistry, Genetics and Molecular Biology