The interaction of stressors in the induction of increased levels of fluctuating asymmetry in the laboratory rat
American Journal of Physical AnthropologyPublished 1 February 1979
Paul W. Sciulli, William J. Doyle, Catherine L. Kelley, P.B. Siegel, Michael I. Siegel
Citations96
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
It was found that all protocols produced higher levels of asymmetry than found for control animals, and noise and reduced protein exhibited an additive effect and the interaction of stressors produced a reduction in litter size.
Abstract
Recent studies on fluctuating dental asymmetry have isolated single stressors as causative agents. Since most stressors are composite in nature, the present study was designed to determine the effects of the interaction of stressors in the induction of fluctuating dental asymmetry. Pregnant rats were assigned to one of six treatment groups and stressed with various combinations of heat, cold, noise and protein deprivation. The levels of fluctuating dental asymmetry were assessed and it was found that all protocols produced higher levels of asymmetry than found for control animals. Noise and reduced protein exhibited an additive effect and the interaction of stressors produced a reduction in litter size. Suggestions were offered for further research in this expanding field.
Keywords
MathematicsEarth and Planetary SciencesBiochemistry, Genetics and Molecular Biology
EvolutionA STUDY OF FLUCTUATING ASYMMETRY
1,459 Citations1962Leigh Van Valen
No new evidence is given as to buffering against environmental stresses of a larger scale, such as temperature or the presence of parasites, but a mean positive correlation between the fluctuating asymmetries of a number of un-
The American Journal of CardiologyThe evolution of the stress concept
596 Citations1970Hans Selye
The inability to find an acute coronary occlusion in a patient who died with manifestations of acute cardiac infarction must not be necessarily ascribed to an oversight on the part of the pathologist.
HeredityGenetical control of stability in development
463 Citations1953Kenneth Mather
In dkEcious animals the decision between male and female development commonly depends on segregation of the X-Y difference, on whether the zygote is carrying XX or XY chromosomes, and in a few species the course of sexual development is switched by external causes.
American Journal of Physical AnthropologyHeat stress, fluctuating asymmetry and prenatal selection in the laboratory rat
113 Citations1977Michael I. Siegel, William J. Doyle +1 more
Prenatal selection with differential survival is suggested as a possible explanation for differences found between the experimental and control animals.
Journal of Experimental ZoologyThe differential effects of prenatal and postnatal audiogenic stress on fluctuating dental asymmetry
105 Citations1975Michael I. Siegel, William J. Doyle
It is shown that there is a limit to the amount of change which can be environmentally induced and that if this limit is reached with prenatal stress, postnatal stress will have no significant effect.
Journal of Experimental ZoologyThe effects of cold stress on fluctuating asymmetry in the dentition of the mouse
96 Citations1975Michael I. Siegel, William J. Doyle
Albino mice (BALB), conceived, born, and raised at 10 degrees C exhibit significant changes in the magnitude of fluctuating dental asymmetry, which confirm the hypothesis that the dentition responds to the general stress syndrome.
American Journal of Physical AnthropologyOn the meaning of increased fluctuating dental asymmetry: A cross populational study
83 Citations1977William J. Doyle, Olivia Johnston
The magnitude of fluctuating dental asymmetry is evaluated for Eskimo and Pueblo populations and these populations were found to exhibit dental variance of equal magnitude to that of the Neandertal population.
American Journal of Physical AnthropologyStress and dental asymmetry in a population of Japanese children
78 Citations1978Robert Dibennardo, Howard L. Bailit
It is concluded that experimental research will be necessary to elucidate not only the determinants of dental asymmetry but the relationship between these determinants and mortality and morbidity.
American Journal of Physical AnthropologyThe effect of extreme temperatures and starvation on the body proportions of the rat
62 Citations1973Alphonse Riesenfeld
A triple experimental approach combined with a two-fold frame of reference (neurocranial length and trunk length) made it possible to differentiate between nutrition-specific and temperature-specific responses under conditions of extreme temperature exposure.
PubMedStress and fluctuating limb asymmetry in various species of rodents.
61 Citations1975Michael I. Siegel, William J. Doyle
None of the stressors employed produced significant increases in fluctuating limb asymmetry except in the humerus, suggesting a stress-related interference in the synchronization of genetically stable structures.
American Journal of Physical AnthropologyNeandertal dental asymmetry and the probable mutation effect
55 Citations1974Brian K. Suarez
If Brace's hypothesis concerning the role of random mutations in structural reduction (PME) is accepted for the sake of argument, then it cannot be used to explain hominid tooth size reduction since the Mousterian because it implies a smaller variance in dental asymmetry for Neandertal than modern man.
PubMedThe effects of audiogenic stress on the growth of long bones in the laboratory rat (Rattus norvegicus).
35 Citations1977Doyle Wj, Carly E. Kelley +1 more
Audiogenic stress is found to produce increases in the magnitude of fluctuating asymmetry of the mass per unit length of long bones in the laboratory rat.
Toxicology and Applied PharmacologyFluctuating dental asymmetry as an indicator of the stressful prenatal effects of Δ9-tetrahydrocannabinol in the laboratory rat
25 Citations1977P.B. Siegel, Michael I. Siegel +3 more
It is concluded that THC was stressful and an alternative to placental transfer, behavioral stress is a possible explanation for this effect.
American Journal of Physical AnthropologyThe effects of stress on cortical bone thickness in rodents
16 Citations1978Maryann Brandt, Michael I. Siegel
It is concluded that stress may be responsible for the thinner cortex of cold and heat stressed animals, but that other factors may be at work and that it is not possible to tell whether different types of stress act through the same or through different mechanisms.
American Journal of Physical AnthropologyCompact bone changes in cold‐exposed rats
5 Citations1976Alphonse Riesenfeld
Rats exposed to cold stress show a reduction of relative cortical thickness in their long bones, which resembles reduction of cortical thickness observed in Asiatic humans of the Mongoloid race.