login

Ovulatory and Metabolic Effects of d-<i>Chiro</i>-Inositol in the Polycystic Ovary Syndrome

New England Journal of MedicinePublished 29 April 1999Open access
John E. Nestler, Daniela Jakubowicz, Paula Reamer, Ronald D. Gunn, Geoffrey Allan
Citations513
SJR quartileQ1
SJR score19.08
SNIP13.47
View PDF

TL;DR

It is hypothesized that the administration of d-chiro-inositol would replenish stores of the mediator and improve insulin sensitivity in 44 obese women with the polycystic ovary syndrome.

Abstract

D-Chiro-inositol increases the action of insulin in patients with the polycystic ovary syndrome, thereby improving ovulatory function and decreasing serum androgen concentrations, blood pressure, and plasma triglyceride concentrations.

Keywords

Medicine