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Amphetamine psychosis: Behavioral and biochemical aspects

Journal of Psychiatric ResearchPublished 1 January 1974
Burton Angrist, Gregory Sathananthan, Sherwin Wilk, Samuel Gershon
Citations327
SJR quartileQ1
SJR score1.49
SNIP1.15

Abstract

Publisher Summary This chapter discusses the behavioral and biochemical aspects of amphetamine psychosis. Amphetamine psychosis was characterized by a brisk emotional reaction, usually in the direction of anxiety amphetamine psychosis was rather strikingly similar to schizophrenia in its presentation; however, these two conditions could be differentiated by the presence of thought disorder that is prominent in schizophrenia and lacking in amphetamine psychosis The pharmacologic manipulation of dopaminergic mechanisms is almost certainly not without effect on other central nervous system systems and certain effects considered dopaminergic may indirectly be mediated by these other systems. Physostigmine can both block and abolish the stereotypy in rats induced by the administration of methylphenidate.

Keywords

MedicineNeuroscience