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Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial

American Journal of PsychiatryPublished 1 April 1997
Gary D. Tollefson, Charles M. Beasley, P.V. Tran, J. Street, J A Krueger, R. Tamura
Citations897
SJR quartileQ1
SJR score5.27
SNIP3.68

TL;DR

Olanzapine shows a superior and broader spectrum of efficacy in the treatment of schizophrenic psychopathology, with a substantially more favorable safety profile, than haloperidol and meets several of the criteria for a novel atypical antipsychotic agent.

Abstract

Olanzapine shows a superior and broader spectrum of efficacy in the treatment of schizophrenic psychopathology, with a substantially more favorable safety profile, than haloperidol. It meets several of the criteria for a novel atypical antipsychotic agent.

Keywords

Medicine