Short-term effect of solidified benzyl benzoate on mite-allergen concentrations in house dust
Journal of Allergy and Clinical ImmunologyPublished 1 January 1991
S. Lau‐Schadendorf, A. Rusche, Anne Weber, Petra Buettner-Goetz, Ulrich Wahn
Citations62
SJR quartileQ1
SJR score3.94
SNIP2.56
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TL;DR
There was a significant reduction of mite allergens in mattresses and carpets within both b b-treated and control groups, but only the results on carpets of the bb-treated group were significantly different from results of the control group on days 30 and 60.
Abstract
The effect of solidified benzyl benzoate (bb) foam and powder on concentrations of the major allergens of Dermatophagoides pteronyssinus (Der p I) and D. farinae (Der f I) in dust samples from mattresses and carpets in 22 households was investigated in a randomized, double-blind, placebo-controlled trial. All houses had been demonstrated to have significant (greater than or equal to 2000 ng/gm of dust) mite-allergen concentrations on mattresses. Dust samples were collected from mattresses and carpets before treatment and on days 10, 30, and 60 after the first treatment. There was a second application on day 10. Der p I and Der f I were determined by a sandwich-type ELISA with monoclonal noncross-reacting antibodies to Der p I and polyclonal monospecific antibodies to Der f I. There was a significant reduction of mite allergens in mattresses and carpets within both bb-treated and control groups, but only the results on carpets of the bb-treated group were significantly different from results of the control group on days 30 and 60 (p less than 0.05).
Keywords
Medicine
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