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Untranslated regions of mRNAs.

Genome BiologyPublished 1 January 2002Open access
Flavio Mignone, Carmela Gissi, Sabino Liuni, Graziano Pesole
Citations971
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TL;DR

Gene expression is finely regulated at the post-transcriptional level through the regulation of stem-loop structures, upstream initiation codons and open reading frames, internal ribosome entry sites and various cis-acting elements that are bound by RNA-binding proteins.

Abstract

Gene expression is finely regulated at the post-transcriptional level. Features of the untranslated regions of mRNAs that control their translation, degradation and localization include stem-loop structures, upstream initiation codons and open reading frames, internal ribosome entry sites and various cis-acting elements that are bound by RNA-binding proteins.

Keywords

Agricultural and Biological SciencesBiochemistry, Genetics and Molecular Biology