Increase of circulating beta-endorphin-like immunoreactivity correlates with the change in feeling of pleasantness after running

Life SciencesPublished 1 March 1986

Johannes Wildmann, Arnd Krüger, Matthias Schmole, J. Niemann, Heinrich Matthaei

DOI10.1016/0024-3205(86)90233-x

Source URL

Citations68

SJR quartileQ1

SJR score1.31

SNIP1.07

TL;DR

There was a significant correlation in the mean values of the two runs between individual beta-EIR increases (delta beta- EIR) and the changes of ratings in feeling of pleasantness (d delta FP), which corresponded to positive mood change post-run.

Abstract

Twenty-one male regular long distance runners participated in two 10 km runs one week apart. Their beta-endorphin-like immunoreactivity (beta-EIR) was assayed in plasma before and immediately after running. Mood was monitored by an adjective check list (Eigenschaftswörterliste, EWL) pre- and post-run. beta-EIR was significantly elevated post-run. Self-reliance and good mood scored higher after running. Both mood elevation and plasma beta-EIR increase showed a considerable individual variability but there was a significant correlation in the mean values of the two runs between individual beta-EIR increases (delta beta-EIR) and the changes of ratings in feeling of pleasantness (delta FP). High delta beta-EIR corresponded to positive mood change post-run.

Keywords

Medicine

Journal of Pharmacology and Experimental TherapeuticsThe effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

2,976 Citations1976W R Martin, C. G. Eades +3 more

It has been shown that buprenorphine is a partial agonist of the mu type which both suppressed and precipitated abstinence in the morphine-dependent dog while morphine and propoxyphene are stronger agonists.

Comprehensive PsychiatryRunning as treatment for depression

374 Citations1979John H. Greist, Marjorie H. Klein +4 more

This work aims to determine whether there is a relationship between exercise and mental health and, if a positive relationship exists, what specific factors under the broader rubric of “exercise” are responsible for its effectiveness in the maintenance and restoration of health.

Life SciencesThe effect of running on plasma β-endorphin

245 Citations1981E Colţ, Sharon L. Wardlaw +1 more

Plasma β-endorphin immunoactivity was measured by RIA in 26 trained long distance runners on 35 occasions before and after running to separate β- endorphin from corssreacting β-lipotropin (β-LPH).

Cellular and Molecular Life SciencesPhysical exercise stimulates marked concomitant release of β-endorphin and adrenocorticotropic hormone (ACTH) in peripheral blood in man

206 Citations1980F. Fraioli, Costanzo Moretti +4 more

The implications of this finding lead to the conclusion that stress stimulates the synthesis of the common precursor in the pituitary, resulting in a marked increase in ACTH and β-endorphin in athletes reaching a status of physical stress.

Journal of Applied PhysiologyIncreases in plasma beta-endorphin/beta-lipotropin immunoreactivity after treadmill running in humans

204 Citations1982Peter A. Farrell, W. K. Gates +2 more

The data suggest that the stress of treadmill running acts as a stimulus to greater Bh-Ep/Bh-LPH secretion, a reduction in its degradation, or a combination of these, which leads to increased levels of these ligands in venous blood.

Psychosomatic MedicinePsychological Changes Accompany Aerobic Exercise in Healthy Middle-Aged Adults

165 Citations1982James A. Blumenthal, Sanders R. Williams +2 more

Results document the potential utility of regular aerobic exercise in promoting psychological health in normal adults and show that the exercisers exhibited less state and trait anxiety, less tension, depression, and fatigue, and more vigor than the controls.

Clinical ScienceThe Role of Opioid Peptides in the Hormonal Responses to Acute Exercise in Man

137 Citations1984Ashley Grossman, P. Bouloux +7 more

Exercise-induced changes in several hormones and metabolites were noted, including elevations in circulating lactate, growth hormone (GH), prolactin, cortisol, luteinizing hormone (LH), follicle stimulating hormone (FSH), adrenaline noradrenaline, plasma renin activity (PRA) and aldosterone.

Medicine & Science in Sports & ExerciseEndorphins and mood changes in long-distance running

126 Citations1982R A Markoff, P. J. Ryan +1 more

The failure of naloxone to reverse the running-associated mood shift indicates that endorphins are not involved, and the authors discuss the possible physiologic role of endorphin in light of these and other findings.

Psychiatry ResearchNaloxone alters pain perception after jogging

120 Citations1981Richard J. Haier, Kimberly A. Quaid +1 more

Life SciencesEndorphin mediated increase in pain threshold induced by long-lasting exercise in rats

104 Citations1982Bai‐Chuang Shyu, S. A. Andersson +1 more

It is suggested that long-lasting muscle exercise (e.g. jogging), acupuncture, and low frequency electrical stimulation of afferent nerve fibres produce discharges in muscle afferents which influence central endorphin mechanisms giving analgetic effects.