Organization of short-term verbal memory in language areas of human cortex: Evidence from electrical stimulation
Brain and LanguagePublished 1 May 1978
George A. Ojemann
Citations169
SJR quartileQ1
SJR score0.93
SNIP1.03
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
There are differential effects of stimulation during input, storage, and output phases of STVM at different cortical sites, which suggest that cortex adjacent to the posterior language area is a site of storage and retrieval from STVM, while cortical adjacent to anteriorlanguage area is involved in retrieval fromSTVM.
Abstract
Short-term verbal memory (STVM) performance was measured during electrical stimulation of human left frontal-parietal-temporal cortex, at craniotomy under local anesthesia for the treatment of medically intractable epilepsy. The areas of cortex where stimulation alters language, as measured by object naming, are separate but adjacent to the areas where stimulation alters STVM. There are differential effects of stimulation during input, storage, and output phases of STVM at different cortical sites. These suggest that cortex adjacent to the posterior language area is a site of storage of STVM, while cortex adjacent to anterior language area is involved in retrieval from STVM.
Keywords
Neuroscience
Journal of Neurology Neurosurgery & PsychiatryLOSS OF RECENT MEMORY AFTER BILATERAL HIPPOCAMPAL LESIONS
7,274 Citations1957William Beecher Scoville, Brenda Milner
It is concluded that the anterior hippocampus and hippocampal gyrus, either separately or together, are critically concerned in the retention of current experience.
Journal of neurosurgeryIntracarotid Injection of Sodium Amytal for the Lateralization of Cerebral Speech Dominance
1,578 Citations1960Jun Wada, Theodore P. Rasmussen
Further studies regarding the technique of intracarotid injection of Sodium Amytal seemed indicated, particularly with regard to the margin of safety in relation to dose and to the effect of accidental injection into the vertebral artery.
NeurosurgeryDisorders of Learning and Memory after Temporal Lobe Lesions in Man
873 Citations1972Brenda Milner
BrainTHE SELECTIVE IMPAIRMENT OF AUDITORY VERBAL SHORT-TERM MEMORY
563 Citations1969Elizabeth K. Warrington, Tim Shallice
Archives of NeurologyMemory and the Hippocampal Complex
335 Citations1966David A. Drachman
Though the two postulated phases of memory have been rechristened, today there is less agreement than ever as to whether a "dualistic" or a "monistic" theory of memory is correct.
Archives of NeurologyMemory
331 Citations1974Wilder Penfield
The cases of two patients who had suffered a grave and totally unexpected loss of recent memory as the result of partial left temporal lobectomy in treatment of focal epilepsy are published.
NeuropsychologiaThe anatomical localisation of selective impairment of auditory verbal short-term memory
283 Citations1971Elizabeth K. Warrington, Valentine Logue +1 more
It has been demonstrated that auditory long-term memory functions are relatively intact, and that the disability is modality-specific to the auditory short-term store.
Brain and LanguageImmediate memory for word lists and sentences in a patient with deficient auditory short-term memory
252 Citations1975Eleanor M. Saffran, Oscar S.M. Marin
This study of a patient with a mild conduction aphasia again traces impaired repetition to faulty auditory short-term memory and shows a remarkable ability to paraphrase sentences he could not repeat verbatim, which has implications for the role of auditory memory in language comprehension.
BrainSPEECH REPRESENTATION IN VENTROLATERAL THALAMUS
214 Citations1971George A. Ojemann, Arthur A. Ward
Archives of NeurologyMemory Loss with Lesions of Hippocampal Formation
192 Citations1961Maurice Victor
In 1888, Sanger-Brown and Schafer 1 described an apparent disturbance of memory in monkeys after the partial or total removal of both temporal lobes, and the matter then lay dormant until 1954, when Scoville 3 described a grave loss of recent memory in 2 patients after resection of the medial parts of bothporal lobes.
Brain and LanguageLanguage and the thalamus: Object naming and recall during and after thalamic stimulation
188 Citations1975George A. Ojemann
Performance on a standard test of object naming, mental arithmetic and recall from short term memory was determined during stimulation of ventrolateral thalamus at the time of stereotaxic thalamotomy and two days after that operation, suggesting that left thalamic stimulation evokes a specific alerting response that directs attention to information in the external environment while simultaneously blocking retrieval from memory.
NeuropsychologiaPersistent anterograde amnesia after stab wound of the basal brain
166 Citations1968Hans‐Lukas Teuber, Brenda Milner +1 more
It is therefore of particular interest that the anterograde amnesia was combined with impotence and profound unresponsiveness to pain.
BrainANOMIA FROM PULVINAR AND SUBCORTICAL PARIETAL STIMULATION
164 Citations1968G. A. Ojemann, Paul Fedio +1 more
Brain and LanguageMemory deficits during electrical stimulation of the speech cortex in conscious man
110 Citations1974Paul Fedio, John M. Van Buren
Cerebral zones supporting language and recent memory were mapped by electrical stimulation during neurosurgical treatment of epileptic patients and produced an anterograde memory loss, apparently caused by a defect in the verbal storage mechanism.
BrainIMPROVEMENT AND DISTURBANCE OF SHORT-TERM VERBAL MEMORY WITH HUMAN VENTROLATERAL THALAMIC STIMULATION
93 Citations1971George A. Ojemann, Katharine I. Blick +1 more
CortexShort-Term Visual and Auditory Memory Disorders After Parietal and Frontal Lobe Damage
91 Citations1970Nelson Butters, Ina Samuels +2 more
The results are interpreted as supporting the notion that the right hemisphere, especially the parietal region, is involved in the processing of visual information, both verbal and patterned, while the left hemisphere is concerned with verbal material irrespective of sensory modality.
Brain and LanguageMemory and perceptual deficits during electrical stimulation in the left and right thalamus and parietal subcortex
90 Citations1975Paul Fedio, John M. Van Buren
An asymmetry in the functional organization of linguistic and nonverbal processes appears to exist at the level of the lateral thalamus, suggesting that the pulvinar scans incoming sensory traces and searches long-term memory registers for appropriate cues and labels.
Journal of neurosurgeryEffect of Stimulation of the Human Thalamus and Parietal and Temporal White Matter on Short-Term Memory
82 Citations1968George A. Ojemann, Paul Fedio
An attempt to determine whether other lateral thalamic and subcortical structures participate in memory functions in patients with electrodes implanted in the thalamus for treatment of motion disorders.
Brain and LanguageShort-term memory and aphasia
56 Citations1976Martin L. Albert
Memory for sequences became critical for linguistic performance of aphasics as information load increased, and memory for sequences was significantly impaired in aphasic only.
Brain and LanguageVerbal retention deficits in aphasic and amnesic patients
54 Citations1976Laird S. Cermak, Judith Moreines
It was discovered that the number of intervening words had a greater effect on the aphasics for all conditions than it did for the other groups, however, when the rate of presentation was slowed, the Aphasics showed considerable improvement while the other patients maintained their same level of performance.
The Journal of Nervous and Mental DiseaseTHE DESTRUCTION OF BOTH ANTERIOR THALAMIC NUCLEI IN A PATIENT WITH INTRACTABLE AGITATED DEPRESSION
28 Citations1970Vernon H. Mark, Herbert Barry +2 more
A patient with chronic intractable agitated depression resistant to psychotherapy, pharmacological agents, and electroshock therapy was presented, and a thorough examination of the patient's brain made it possible to make an anatomical clinical correlation of anterior thalamic nucleus function.
NeuropsychologiaLearning in dysphasia
18 Citations1970G. Ettlinger, A. Moffett
It was found that learning a sequence of object names facilitates, but generally does not ensure perfect performance at, object naming, and suggest that there might co-exist two disabilities in dysphasia: verbal learning and verbal recall.
NeuropsychologiaAlteration in nonverbal short term memory with stimulation in the region of the mammillothalamic tract in man
17 Citations1971George A. Ojemann
Cette constatation est en faveur du modele de the lateralisation de the fonction de memoire a court terme, les structures cerebrales droites etant concernees avec the memoirea a court Terme non verbale.