A Multistate, Foodborne Outbreak of Hepatitis A
New England Journal of MedicinePublished 25 February 1999Open access
Yvan Hutin, Vitali Pool, Elaine H. Cramer, Omana V. Nainan, Jo Weth, Ian T. Williams
Citations387
SJR quartileQ1
SJR score19.08
SNIP13.47
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
A large outbreak of hepatitis A in Michigan that was associated with the consumption of frozen strawberries is described and apparently sporadic cases in other states that could be linked to the same source by viral genetic analysis are found.
Abstract
We describe a large outbreak of hepatitis A in Michigan that was associated with the consumption of frozen strawberries. We found apparently sporadic cases in other states that could be linked to the same source by viral genetic analysis.
Keywords
MedicineAgricultural and Biological SciencesBiochemistry, Genetics and Molecular Biology
Nucleic Acids ResearchA comprehensive set of sequence analysis programs for the VAX
14,423 Citations1984John Devereux, Paul Haeberli +1 more
A group of programs that will interact with each other has been developed for the Digital Equipment Corporation VAX computer using the VMS operating system.
Clinical Microbiology ReviewsEpidemiology of human listeriosis
636 Citations1991Anne Schuchat, B. Swaminathan +1 more
Current research application of new molecular methods to the study of L. monocytogenes may improve the ability to diagnose pregnancy-associated disease and permit the rapid detection and control of Listeriosis in the food supply.
Journal of General VirologyGenetic relatedness of hepatitis A virus strains recovered from different geographical regions
495 Citations1992Betty H. Robertson, Robert W. Jansen +11 more
A pairwise comparison of the nucleic acid sequence of 168 bases from 152 wild-type or unique cell culture-adapted strains of hepatitis A virus (HAV) revealed that HAV strains can be differentiated genetically into seven unique genotypes (I to VII), indicating that patterns of endemic transmission can be distinguished from situations in which infections are imported due to travel.
Journal of VirologyComplete nucleotide sequence of wild-type hepatitis A virus: comparison with different strains of hepatitis A virus and other picornaviruses
381 Citations1987Jeffrey I. Cohen, John R. Ticehurst +3 more
HAV proteins are less homologous with those of any other picornavirus than the latter proteins are when compared with each other, and when the sequences of wild-type and cell culture-adapted HAV strains are compared, the nucleotide Differences in the 5' noncoding region and the amino acid differences in the capsid region suggest areas that may contain markers for cell culture adaptation and for attenuation.
The Journal of Infectious DiseasesMultistate Outbreak of Hepatitis A Associated with Frozen Strawberries
241 Citations1992Manette T. Niu, Louis B. Polish +9 more
Molecular analysis of HAV from patients in the two outbreaks revealed that the viral genomes were genetically identical and distinct from other known US strains and should be considered in investigating common-source outbreaks of hepatitis A.
The Journal of Infectious DiseasesThe Diverse Patterns of Hepatitis A Epidemiology in the United States—Implications for Vaccination Strategies
227 Citations1998Beth P. Bell, Craig N. Shapiro +7 more
During communitywide outbreaks, hepatitis A is not limited to specific risk groups; sustained nationwide reductions in incidence are more likely to result from routine childhood vaccination than from targeted vaccination of high-risk groups.
American Journal of Public HealthA multifocal outbreak of hepatitis A traced to commercially distributed lettuce.
213 Citations1990Lisa Rosenblum, Irene R. Mirkin +3 more
This outbreak of hepatitis A is the first in the United States apparently associated with fresh produce contaminated before distribution to restaurants, and raises important public health issues regarding the regulation of fresh produce.
American Journal of Public HealthA multistate outbreak of hepatitis A caused by the consumption of raw oysters.
197 Citations1991J C Desenclos, Karl C. Klontz +4 more
Epidemiology and InfectionFrozen raspberries and hepatitis A
161 Citations1987Thomas M. Reid, H. G. Robinson
Food-specific questioning of those affected, their fellow diners and hotel staff, coupled with serological studies, implicated raspberry mousse prepared from frozen raspberries as the source of the infection.
BMJInternational epidemiological and microbiological study of outbreak of Salmonella agona infection from a ready to eat savoury snack—I: England and Wales and the United States
155 Citations1996Dan Killalea, Ward Lr +13 more
The Salm-Net surveillance system and its links outside Europe showed the value of increasing case ascertainment and for improving the information on the duration of the fault at the manufacturing plant in an international outbreak of food poisoning due to Salmonella agona phage type 15.
New England Journal of MedicineSurveillance for<i>Escherichia coli</i>O157:H7 Infections in Minnesota by Molecular Subtyping
147 Citations1997Jeffrey B. Bender, Craig W. Hedberg +4 more
Subtype-specific surveillance for E. coli O157:H7 can identify outbreaks that are not detected by traditional methods and can ascertain whether sudden increases in reported cases are due to sporadic isolated cases or to one or more outbreaks.
Journal of Clinical MicrobiologySurvival of hepatitis A virus in feces after drying and storage for 1 month
140 Citations1982Karen A. McCaustland, Walter W. Bond +3 more
Hepatitis A virus in feces remained viable after being dried and then stored at 25 degrees C and 42% relative humidity for 30 days, as evidenced by infection of two marmosets inoculated with 1 ml of the treated fecal material.
JAMAOyster-Associated Hepatitis
110 Citations1975Benjamin L. Portnoy
During October and November 1973, outbreaks of hepatitis A associated with consumption of raw oysters occurred in Houston and in Calhoun, Ga.
Journal of General VirologySequence analysis of a new hepatitis A virus naturally infecting cynomolgus macaques (Macaca fascicularis)
90 Citations1991Omana V. Nainan, Harold S. Margolis +3 more
The Journal of Infectious DiseasesFood-borne Hepatitis A: Recommendations for Control
43 Citations1983M Carl, D. P. Francis +1 more
Twenty foodborne outbreaks of hepatitis A that occurred in the United States during 1968-1980 were examined, in which a source case or presumed source case was identified, by a review of all published outbreaks reported to the CDC.
JAMAOyster-associated hepatitis. Failure of shellfish certification programs to prevent outbreaks
39 Citations1975B. L. Portnoy
Journal of Virological MethodsSequence-specific, single-primer amplification and detection of PCR products for identification of hepatitis viruses
33 Citations1996Omana V. Nainan, Theresa L. Cromeans +1 more
The sensitivity of this assay for the detection of hepatitis A virus, hepatitis B virus, and hepatitis C virus is equal to that of existing nucleic acid detection systems.
