Estrogen Protection against Bone Resorbing Effects of Parathyroid Hormone Infusion: Assessment by Use of Biochemical Markers
Annals of Internal MedicinePublished 1 March 1993
Felicia Cosman, Victor Shen, Fang Xie, Markus Seibel, Anthony Ratcliffe, Robert Lindsay
Citations140
SJR quartileQ1
SJR score3.38
SNIP3.27
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TL;DR
These findings support the hypothesis that estrogens can directly affect skeletal metabolism through osteoblasts, osteoclasts, or both and determine in a systematic fashion whether estrogen induced resistance to the skeletal remodeling effects of PTH.
Abstract
The estrogenized postmenopausal osteoporotic skeleton is less sensitive to the bone resorbing effects of acutely administered PTH. There are no differential effects on bone formation.
Keywords
Medicine