Hepatocellular Carcinoma Caused by Hepatitis B Virus

Hepatocellular carcinoma is more common in males than among females, and its prevalence increases with age, although in high-risk populations, the disease also occurs in younger age groups.

Abstract

Although hepatocellular carcinoma (HCC) is rare in Europe and North America, it is very common in many areas of the world, especially in Africa and southeast Asia, where it is among the ten most common human cancers. It is estimated that there are more than 500,000 new patients with liver cancer each year. Over 30 new cases of hepatoma occur per 100,000 population annually in the high-prevalence areas, but the yearly incidence is less than 5 per 100,000 in most countries of North America, Europe, and Australia. Hepatocellular carcinoma is more common in males than among females. Its prevalence increases with age, although in high-risk populations, the disease also occurs in younger age groups.