The March of AIDS through Asia
New England Journal of MedicinePublished 1 August 1996
Bruce G. Weniger, Tim Brown
Citations53
SJR quartileQ1
SJR score19.08
SNIP13.47
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
A modest victory in what had been a losing battle in northern Thailand to control the most rapid epidemic of sexually transmitted human disease is described.
Abstract
In this issue of the Journal, Nelson and colleagues1 describe a modest victory in what had been a losing battle in northern Thailand to control the most rapid epidemic of sexually transmitted human immunodeficiency virus (HIV) infection ever documented.2 Studying large cohorts of randomly selected conscripts in the Royal Thai Army, they report a significant downturn in the prevalence of HIV infection, from a peak of about 13 percent to less than 7 percent, which is also reflected in national trends.3 Although the rate of infection remains serious, this encouraging sign reflects the effect of an enlightened effort in many . . .
Keywords
Medicine
AIDSThe epidemiology of HIV infection and AIDS in Thailand
421 Citations1991Bruce G. Weniger, Khanchit Limpakarnjanarat +7 more
The authors note that the scenario of HIV transmission observed in Thailand also seems to be unfolding in neighboring countries, and HIV infection among female prostitutes and heterosexual men is consistently highest in the northern Thai provinces adjacent to Myanmar and Laos.
ScienceAIDS: an International Perspective
390 Citations1988Peter Piot, Francis A. Plummer +4 more
Heterosexual transmission appears to be increasing in some parts of Latin America and the Caribbean, and possibly in the United States, and at least one other human retrovirus, namely HIV-2, has been implicated as a cause of AIDS in Africa and Europe.
New England Journal of MedicineChanges in Sexual Behavior and a Decline in HIV Infection among Young Men in Thailand
366 Citations1996Kenrad E. Nelson, David D. Celentano +6 more
Public health programs in Thailand have led to substantial changes in sexual behavior among young men, especially an increased use of condoms, and the rate of new HIV infections has declined.
ScienceHIV-1 Langerhans' Cell Tropism Associated with Heterosexual Transmission of HIV
348 Citations1996Luis Enrique Soto-Ramírez, Boris Renjifo +15 more
Results suggest that LC tropism is associated with the efficiency of heterosexual transmission of HIV, which is less important in the HIV-1 epidemics of the United States and Western Europe.
Sexually Transmitted DiseasesThe Association Between Lack of Male Circumcision and Risk for HIV Infection
135 Citations1994Stephen Moses, Francis A. Plummer +4 more
Because a substantial body of evidence links noncir-cumcision in men with risk for HIV infection, consideration should be given to male circumcision as an intervention to reduce HIV transmission.
AIDSExperience from HIV incidence cohorts in Thailand
114 Citations1994Bruce G. Weniger
The documented circulation of 2 distinct subtypes of HIV-1 in Thailand would permit vaccine trials that could measure cross-protection against wild viruses genetically heterologous to vaccine antigen.
Mathematical Medicine and Biology A Journal of the IMABalancing sexual partnership in an age and activity stratified model of HIV transmission in heterosexual populations
110 Citations1994Geoffrey P. Garnett, Roy M. Anderson
The analysis of the sensitivity of predictions to changing parameters in the force of infection term of the model provides a theoretical basis from which the influence of control strategies and the demographic effects of HIV can be analysed.
AIDSDeclining prevalence of HIV-1 infection in young Thai men
83 Citations1995Carl J. Mason, Lauri E. Markowitz +8 more
The decline in prevalence suggests declining incidence and that HIV control programs in Thailand are having an impact on the HIV epidemic.
AIDSHeparin specifically inhibits binding of V3 loop antibodies to HIV-1 gp120, an effect potentiated by CD4 binding
67 Citations1994Hilary A. Harrop, Deirdre R. Coombe +1 more
Heparin is more selective and appears to function only by interfering with events involving the V3 loop that occur prior to HIV fusion with the plasma membrane, whereas heparin has no effect.
AIDSNormal triglyceride levels in early HIV-1 infection
39 Citations1994Marianna K. Baum, Gail Shor‐Posner +1 more
AIDS CareAIDS awareness among a cohort of young Thai men: Exposure to information, level of knowledge, and perception of risk
26 Citations1995Michael Sweat, Taweesak Nopkesorn +6 more
Multivariate PATH analysis shows that exposure to information about AIDS significantly reduced risk taking from baseline to follow-up, but only by first affecting personal risk perception.