A bird's eye view of global methylation
Nature GeneticsPublished 1 February 2000Open access
Charis Eng, James G. Herman, Stephen B. Baylin
Citations61
SJR quartileQ1
SJR score16.59
SNIP6.64
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TL;DR
This and other genome-scanning approaches allows the rapid analysis of methylation profiles of thousands of genes in parallel—and promises to identify new genes critical to carcinogenesis and other biological processes.
Abstract
Restriction landmark genomic scanning applied to a broad variety of cancer types can disclose tumour-specific and tumour-type-specific global methylation profiles. This and other genome-scanning approaches allows the rapid analysis of methylation profiles of thousands of genes in parallel-and promises to identify new genes critical to carcinogenesis and other biological processes.
Keywords
Biochemistry, Genetics and Molecular Biology
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