Anorexia of infection as a mechanism of host defense
American Journal of Clinical NutritionPublished 1 March 1979
MJ Murray, AB Murray
Citations312
SJR quartileQ1
SJR score2.11
SNIP1.75
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TL;DR
It is suggested that anorexia, by reducing energy intake, has a significant role in the early defense of the host.
Abstract
The role of anorexia of infection as a mechanism of host defense was studied by force-feeding infected mice to a normal energy intake. Their mortality and survival times were then compared with those of infected mice feeding ad libitum. Mortality was increased and survival time shortened in force fed animals. Our observations suggest that anorexia, by reducing energy intake, has a significant role in the early defense of the host.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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